Resource:The World Lab
|Name:||Resource:The World Lab|
A substantial biological challenge is to understand the regulation and execution of developmental decisions that lead from multipotential, undifferentiated precursor cells to their specialized differential products. In the Wold lab at the California Institute of Technology, we are interested in several interrelated aspects of this problem, and we also work to develop new methods for studying it. The particular cell lineage problem we study begins with the specification of mesoderm in early development and continues to the final differentiation of skeletal muscle or cardiac muscle in the fully developed animal. To study this process we use the mouse as our experimental system. Molecular-level analyses use cell culture model systems and transgenic mice. These projects include studies of in vitro and in vivo protein-DNA interactions and of factors that amplify or suppress expression activity. Computational approaches involve the development of algorithms for use in large-scale gene expression analysis and the construction of a simulator framework for regulation in muscle development.
|Other Name(s):||World Lab|
|Parent Organization:||California Institute of Technology; California; USA|
|Resource Type(s):||laboratory portal (birnlex_2370), web accessible database (nlx_res_090910)|
|Link to OWL / RDF:||Download this content as OWL/RDF|
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A substantial biological challenge …
or regulation in muscle development.
|Has default formThis property is a special property in this wiki.||Resource +|
|Has role||Laboratory portal (birnlex 2370) +, and Web accessible database (nlx res 090910) +|
|Is part of||California Institute of Technology; California; USA +|
|Label||Resource:The World Lab +|
|ModifiedDate||18 May 2011 +|
|Page has default formThis property is a special property in this wiki.||Resource +|
|Synonym||World Lab +|