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Synapse

Name: Synapse
Description: The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane (Gene Ontology).
Synonym(s): synaptic junction
Super-category: Cellular component
*Id: GO:0045202
Publication link: http://amigo.geneontology.org/amigo/term/GO:0045202
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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

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CommentWe do not agree with GO that electronic synapse or mixed synapse are synonyms of "Synapse": they are types of synapses. Also, there is the immunological synapse.
CurationStatuspending final vetting  +
CuratorMaryann Martone  +
DefinitionThe junction between a nerve fiber of one The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane (Gene Ontology). the postsynaptic membrane (Gene Ontology).
IdGO:0045202  +
LabelSynapse  +
ModifiedDate24 July 2014  +
PublicationLinkhttp://amigo.geneontology.org/amigo/term/GO:0045202  +
SuperCategoryCellular component  +
Synonymsynaptic junction  +