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Tyrosine Hydroxylase

Name: Tyrosine Hydroxylase
Description: Tyrosine Hydroxylase is a synthetic enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen (Fe2+ is a cofactor) to 3,4-dihydroxy-L-phenylalanine (L-DOPA), dihydrobiopterin, and water. EC 1.14.16.2 (MSH). It is the rate-limiting enzyme in catecholamine synthesis, presumable because its maximum velocity is slower than that of any of the other enzymes in the synthetic pathway.
Synonym(s): 3-Monooxygenase, Tyrosine; Hydroxylase, Tyrosine; Tyrosine Hydroxylase; Tyrosine 3 Monooxygenase; L-Tyrosine, tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating);TYROSINE MONOOXYGENASE 003; Tyrosine 3 Monooxygenase;
Is part of: Catecholamine system, Adrenergic system, Dopaminergic system, Noradrenergic system
Related to: Tyrosine, Tetrahydrobiopterin, L-Dopa, dopamine
Has role: Synthetic Enzyme
Abbreviation: TH
Super-category: Protein
URL: Medical Subject Headings
Id: sao289587392
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  • Has role: Synthetic Enzyme


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Facts about Tyrosine HydroxylaseRDF feed
AbbrevTH  +
CurationStatusuncurated  +
DefiningCitationMedical Subject Headings  +
DefinitionTyrosine Hydroxylase is a synthetic enzyme Tyrosine Hydroxylase is a synthetic enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen (Fe2+ is a cofactor) to 3,4-dihydroxy-L-phenylalanine (L-DOPA), dihydrobiopterin, and water. EC 1.14.16.2 (MSH). It is the rate-limiting enzyme in catecholamine synthesis, presumable because its maximum velocity is slower than that of any of the other enzymes in the synthetic pathway. he other enzymes in the synthetic pathway.
Has roleSynthetic Enzyme  +
Idsao289587392  +
Is part ofCatecholamine system  +, Adrenergic system  +, Dopaminergic system  +, and Noradrenergic system  +
LabelTyrosine Hydroxylase  +
ModifiedDate28 January 2011  +
RelatedToTyrosine  +, Tetrahydrobiopterin  +, L-Dopa  +, and Dopamine  +
SuperCategoryProtein  +
Synonym3-Monooxygenase  +, Tyrosine; Hydroxylase  +, Tyrosine; Tyrosine Hydroxylase; Tyrosine 3 Monooxygenase; L-Tyrosine  +, and tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating);TYROSINE MONOOXYGENASE 003; Tyrosine 3 Monooxygenase;  +