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Tyrosine Hydroxylase
| Name: | Tyrosine Hydroxylase |
| Description: | Tyrosine Hydroxylase is a synthetic enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen (Fe2+ is a cofactor) to 3,4-dihydroxy-L-phenylalanine (L-DOPA), dihydrobiopterin, and water. EC 1.14.16.2 (MSH). It is the rate-limiting enzyme in catecholamine synthesis, presumable because its maximum velocity is slower than that of any of the other enzymes in the synthetic pathway. |
| Synonym(s): | 3-Monooxygenase, Tyrosine; Hydroxylase, Tyrosine; Tyrosine Hydroxylase; Tyrosine 3 Monooxygenase; L-Tyrosine, tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating);TYROSINE MONOOXYGENASE 003; Tyrosine 3 Monooxygenase; |
| Is part of: | Catecholamine system, Adrenergic system, Dopaminergic system, Noradrenergic system |
| Related to: | Tyrosine, Tetrahydrobiopterin, L-Dopa, dopamine |
| Has role: | Synthetic Enzyme |
| Abbreviation: | TH |
| Super-category: | Protein |
| URL: | Medical Subject Headings |
| Id: | sao289587392 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
- Has role: Synthetic Enzyme
Facts about Tyrosine HydroxylaseRDF feed
| Abbrev | TH + |
| CurationStatus | uncurated + |
| DefiningCitation | Medical Subject Headings + |
| Definition | Tyrosine Hydroxylase is a synthetic enzyme … Tyrosine Hydroxylase is a synthetic enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen (Fe2+ is a cofactor) to 3,4-dihydroxy-L-phenylalanine (L-DOPA), dihydrobiopterin, and water. EC 1.14.16.2 (MSH). It is the rate-limiting enzyme in catecholamine synthesis, presumable because its maximum velocity is slower than that of any of the other enzymes in the synthetic pathway. he other enzymes in the synthetic pathway. |
| Has role | Synthetic Enzyme + |
| Id | sao289587392 + |
| Is part of | Catecholamine system +, Adrenergic system +, Dopaminergic system +, and Noradrenergic system + |
| Label | Tyrosine Hydroxylase + |
| ModifiedDate | 28 January 2011 + |
| RelatedTo | Tyrosine +, Tetrahydrobiopterin +, L-Dopa +, and Dopamine + |
| SuperCategory | Protein + |
| Synonym | 3-Monooxygenase +, Tyrosine; Hydroxylase +, Tyrosine; Tyrosine Hydroxylase; Tyrosine 3 Monooxygenase; L-Tyrosine +, and tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating);TYROSINE MONOOXYGENASE 003; Tyrosine 3 Monooxygenase; + |