Molecule Table
From NeuroLex
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| Synonym | Definition | Comment | |
|---|---|---|---|
| 11-dehydro-thromboxane B2 | |||
| 2-Chloro-Adenosine 5'-diphosphate | |||
| 2-methylthio adenosine 5'-diphosphate | |||
| 2-methylthio adenosine 5'-triphosphate | |||
| 5-HT1A receptor | 5-HT1A; 5- HT1A; 5-HT-1A; G-21; Serotonin receptor 1A; 5-hydroxytryptamine 1A receptor | ||
| 5-HT1B receptor | 5-HT1B;5- HT1B; 5-HT-1B; 5-HT-1D-beta; S12; Serotonin 1D beta receptor; Serotonin receptor 1B; 5-hydroxytryptamine 1B receptor | ||
| 5-HT1D receptor | 5-HT1D; 5- HT-1D-alpha; 5-HT-1D; Serotonin receptor 1D; 5-hydroxytryptamine 1D receptor | ||
| 5-HT1E receptor | 5-HT1E; 5- HT1E; 5-HT-1E; S31; Serotonin receptor 1E; 5-hydroxytryptamine 1E receptor | ||
| 5-HT1F receptor | 5-HT1F; 5-HT-1F; Serotonin receptor 1F; 5-hydroxytryptamine 1F receptor | ||
| 5-HT2A receptor | 5-HT2A; 5- HT-2; 5-HT-2A; Serotonin receptor 2A; 5-hydroxytryptamine 2A receptor | ||
| 5-HT2B receptor | 5-HT2B;5-HT-2B; Serotonin receptor 2B; 5-hydroxytryptamine 2B receptor | ||
| 5-HT2C receptor | 5-HT2C;5- HT2C; 5-HT-2C; 5-HTR2C; 5HT-1C; Serotonin receptor 2C; 5-hydroxytryptamine 2C receptor | ||
| 5-HT4 receptor | 5-HT4; 5- HT4; 5-HT-4; Serotonin receptor 4; 5-hydroxytryptamine 4 receptor | ||
| 5-HT5A receptor | 5-HT5A | ||
| 5-HT6 receptor | 5-HT6; 5-HT-6; Serotonin receptor 6; 5-hydroxytryptamine 6 receptor | ||
| 5-HT7 receptor | 5-HT7; 5-HT- X; 5-HT-7; 5HT7; Serotonin receptor 7; 5-hydroxytryptamine 7 receptor | ||
| 5-oxo-6,8,11,14-eicosatetraenoic acid | |||
| A1 receptor | A1; Adenosine A1 receptor | ||
| A2A receptor | A2A; Adenosine A2a receptor | ||
| A2B receptor | A2B; Adenosine A2b receptor | ||
| A3 receptor | A3; Adenosine A3 receptor | ||
| ABC transporter | |||
| ALX receptor | ALX | ||
| AMPA-type glutamate-gated cationic channel | AMPA receptor AMPA |
Cell surface proteins that bind glutamate and directly gate ion channels in cell membranes. AMPA receptors were originally discriminated from other glutamate receptors by their affinity for the agonist AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid). They are probably the most common mediators of fast excitatory synaptic transmission in the central nervous system. Several subtypes have been cloned, and for some types the traditional distinction from kainate receptors may not apply (MSH). | |
| ANKTM1 | ankyrin-like with transmembrane domains 1 | ||
| ANT-1 | |||
| ANT-2 | |||
| APJ receptor | APJ | ||
| AT1 receptor | AT1 | ||
| AT2 receptor | AT2 | ||
| ATP-gated ion channel | P2X receptor-linked ion channel ATP2x receptor-linked ion channel ATP2x receptor P2X receptor |
||
| Acetate | |||
| Acetylcholine | ACh | A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, but it is useful in some ophthalmological applications (MSH). | |
| Acetylcholine (muscarinic) receptor | mAChR Muscarinic ACh receptor Muscarinic AChR MAChR Muscarinic acetylcholine receptor |
One of the two major classes of cholinergic receptors. Muscarinic receptors were originally defined by their preference for MUSCARINE over NICOTINE. There are several subtypes (usually M1, M2, M3....) that are characterized by their cellular actions, pharmacology, and molecular biology. Year introduced: 1984(1977) - adapted from MeSH | |
| Acetylcholine Receptor | cholinergic receptor AChR |
Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology (MSH). | |
| Acetylcholine-gated channel (nicotinic) | Nicotinic acetylcholine receptor nAChR |
This is an acetylcholine binding, cationic channel, which is primarily found on the muscle tissue of vertebrates. | |
| Acetylcholinesterase | Acetylcholine esterase | An enzyme that catalyzes the hydrolysis of acetylcholine to choline and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7. (MSH) | |
| Actin | Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle (MSH). | ||
| Adenine Nucleotide Transporter | Transports adenine nucleotides (AMP, ADP, and ATP) across membranes (Gene Ontology). | ||
| Adenosine 3',5'-cyclic monophosphate | |||
| Adenosine 5'-O-(2-fluoro)-diphosphate | |||
| Adenosine 5'-O-(2-thio)-diphosphate | |||
| Adenosine 5'-O-(3-thio)-triphosphate | |||
| Adenosine 5'-diphosphate | |||
| Adenosine 5'-monophosphate | |||
| Adenosine 5'-triphosphate | |||
| Adenosine receptor | |||
| Adrenoceptor receptor | Alpha-adrenergic receptor Alpha adrenergic receptor Beta-adrenergic receptor Beta adrenergic receptor |
Class of G-protein receptors that are activated by catecholamines. | |
| Adrenocorticotropic hormone | |||
| Adrenomedullin | |||
| Allograft inflammatory factor 1 | Ionized calcium-binding adapter molecule 1 Microglia response factor |
a small 17-kDa protein consisting of 147 amino acids. It contains two EF hand motifs in the central third of the molecule. | |
| Alpha 3 Acetylcholine Receptor | Neuronal Acetylcholine Receptor Subunit Alpha-3 CHRNA3 NACHRA3 Cholinergic receptor nicotinic alpha 1 |
Neuronal acetylcholine receptor subunit alpha-3 is encoded by the human CHRNA3 gene. This protein plays a role in ion transport. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly. (Adapted from NCBI and Swiss-Prot). | |
| Alpha 7 Acetylcholine Receptor | Acra7 Acetylcholine Receptor Alpha 7 CHRNA7 Cholinergic receptor nicotinic alpha 7 Neuronal acetylcholine receptor subunit alpha-7 α7 receptor |
||
| Alpha Actinin | Cytoskeletal protein present in Z lines of muscle fibrils and at sites of non-muscle cell contact with a substrate (CSP). | ||
| Alpha Tubulin | One of two globular polypeptides forming microtubules. | ||
| Alpha bungarotoxin | A type of bungarotoxin derived from the venom of the Taiwanese cobra Bugarus multicinctus. It is a peptide of 74 amino acids that bind to the nicotinic acetylcholine receptor with high affinity. | ||
| Alpha-Synuclein DNA | The alpha-Synuclein gene is mapped to human chromosome 4q21.3-q22 and organized as seven exons, five of which are protein-coding. | ||
| Alpha-Synuclein Protein | NACP Nonamyloid Component of Plaques Precursor Protein |
Predominantly a presynaptic neuronal protein of unknown function, but can also be found in glial cells. Expressed particularly in the neocortex, hippocampus, striatum, thalamus, and cerebellum. It is normally an unstructured protein yet it can aggregate to form incoluble fibrils in pathological conditions characterized by Lewy bodies. It is the primary structural component of Lewy body fibrils and an alpha-synuclein fragment, known as the non-ABeta component (NAC) is found in amyloid plaques. | |
| Alpha-Synuclein RNA | The alpha-Synuclein mRNA is targeted when researchers target alpha-Synuclein gene expression. | ||
| Alpha-ketoglutarate | a-ketoglutarate | ||
| Alpha-melanocyte stimulating hormone | a-melanocyte stimulating hormone | ||
| Alpha1A receptor | alpha1A; alpha 1A A1A; Alpha 1A- adrenoreceptor; Alpha 1A-adrenoceptor; Alpha adrenergic receptor 1c; Alpha-1C adrenergic receptor; Alpha-1A adrenergic receptor |
Adrenergic receptor with high affinity binding to WB-4101. | |
| Alpha1B receptor | alpha1B alpha 1B A1B; Alpha 1B- adrenoreceptor; Alpha 1B-adrenoceptor; Alpha-1B adrenergic receptor |
Alpha adrenergic receptor with a lower affinity for WB-4101. | |
| Alpha1D receptor | alpha1D; alpha 1D; A1D; Alpha 1D- adrenoreceptor; Alpha 1D-adrenoceptor; Alpha adrenergic receptor 1a; Alpha-1A adrenergic receptor; Alpha-1D adrenergic receptor | Alpha adrenergic receptor that is found in the rat aorta, and is genetically different from the other alpha1 receptors. | |
| Alpha2A receptor | alpha2A; alpha 2A; A2A; Alpha-2 adrenergic receptor subtype C10; Alpha-2A adrenoceptor; Alpha-2A adrenoreceptor; Alpha-2AAR; Alpha-2A adrenergic receptor | Alpha adrenergic receptor that is found in platelets and has a low affinity for prazosin. | |
| Alpha2B receptor | alpha2B; alpha 2B; A2B; Alpha-2 adrenergic receptor subtype C2; Alpha-2B adrenoceptor; Alpha-2B adrenoreceptor; Alpha-2B adrenergic receptor | Alpha adrenergic receptor found in neonatal rat lung that has a high affinity for prazosin. | |
| Alpha2C receptor | alpha2C; alpha 2C; A2C; Alpha-2 adrenergic receptor subtype C4; Alpha-2C adrenoceptor; Alpha-2C adrenoreceptor; Alpha-2C adrenergic receptor | ||
| Alpha2D receptor | Alpha2D Alpha 2D A2D |
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| Amino Acid | Amino acids | Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins (MSH). | |
| Aminoalkylindole | |||
| Amylin | |||
| Amyloid Precursor Protein | APP amyloid beta (A4) precursor protein Amyloid beta A4 protein Alzheimer disease amyloid protein |
A membrane protein expressed in many tissues and concentrated in the synapses of neurons. It is implicated as a regulator of synapse formation and neural plasticity. Its proteolysis generates amyloid beta. | |
| Amyloid Protein | Fibrous protein with insoluble fibrils that generally resist proteolytic digestion. | ||
| Anaphylatoxin C3a | |||
| Anaphylatoxin C5a | |||
| Anaphylatoxin receptor | |||
| Anaphylatoxin receptor - unspecified 1 | |||
| Anaphylatoxin receptor - unspecified 2 | |||
| Anaphylatoxin receptor - unspecified 3 | |||
| Angiotensin | |||
| Angiotensin receptor | |||
| Anionic cys-loop ligand-gated ion channel | |||
| Antibody | antibodies immunoglobulin |
An antibody is any of the structurally related proteins that function as immunoglobulins. They are divided into five classes (IGA, IGD, IGE, IGG, IGM) on the basis of structure and biological activity. | |
| Apelin | |||
| Apelin receptor | |||
| Apolipoprotein | |||
| Apolipoprotein E | Apo-E; Apolipoprotein E precursor; Apolipoprotein E | ||
| Apolipoprotein J | |||
| Aquaporin 4 | |||
| Arachidonic acid | (5Z 8Z 11Z 14Z)-icosa-5 8 11 14-tetraenoic acid |
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| Aspartate | HO2CCH(NH2)CH2CO2H Aspartic acid |
the carboxylate anion of aspartic acid and the L-isomer of aspartate is one of the 20 proteinogenic amino acids, i.e., the building blocks of proteins. Its codons are GAU and GAC. (adapted from Wikipedia) | |
| B1 receptor | B1 | ||
| B2 receptor | B2; B2R; BK-2 receptor; B2 bradykinin receptor | ||
| BAM8-22 | |||
| BB1 receptor | BB1 | ||
| BB2 receptor | BB2 | ||
| BB3 receptor | BB3 | ||
| BDNF | brain-derived neurotrophic factor | ||
| BLT1 receptor | BLT1 | ||
| BLT2 receptor | BLT2 | ||
| Beta Neurexin | |||
| Beta Tubulin | One of two globular polypeptides forming microtubules. | ||
| Beta secretase | an aspartic-acid protease important in the pathogenesis of Alzheimer's disease, and in the formation of myelin sheaths in peripheral nerve cells. The transmembrane protein, contains two active site aspartate residues in its extracellular protein domain and may function as a dimer. | ||
| Beta secretase 1 | Memapsin-2 | ||
| Beta secretase 2 | |||
| Beta-Amyloid | Amyloid-Beta Amyloid Beta Beta Amyloid Aβ Abeta |
A 39-43 amino acid peptide composed of 11-15 amino acids of the transmembrance domain of amyloid precursor protein (APP). | |
| Beta-Amyloid 40 | Amyloid-Beta 40 | ||
| Beta-Amyloid 42 | Amyloid-Beta 42 | ||
| Beta-Synuclein Protein | PNP14 Phosphoneuroprotein 14 |
A synuclein protein found primarily in brain tissue and seen mainly in presynaptic terminals. It is predominantly expressed in the neocortex, hippocampus, striatum, thalamus, and cerebellum. It is not found in lewy bodies, but it is associated with hippocampal pathology in Parkinson's disease and dimentia with Lewy bodies. | |
| Beta-alanine | b-alanine | ||
| Beta-endorphin | b-endorphin | ||
| Beta-melanocyte stimulating hormone | b-melanocyte stimulating hormone | ||
| Beta-phenylethylamine | b-phenylethylamine | ||
| Beta1 receptor | beta1; Beta 1; B1; Beta-1 adrenoceptor; Beta-1 adrenoreceptor; Beta-1 adrenergic receptor | Beta Adrenergic receptor with approximately equal affinity for epinephrine and norepinephrine. | |
| Beta2 receptor | beta2; beta 2; b2; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; Beta-2 adrenergic receptor | Beta adrenergic receptor with 100-fold greater affinity for epinephrine than norepinephrine. | |
| Beta2 receptor (nifext 7082) | |||
| Beta3 receptor | beta3; beta 3; b;3Beta-3 adrenoceptor; Beta-3 adrenoreceptor; Beta-3 adrenergic receptor | Beta adrenergic receptor found in brown adipose tissue, which stimulates lipolysis and thermogenesis. This receptor class has a low affinity for beta1 and beta2 receptors, but a high affinity for BRL 37344 and its derivatives. | |
| Bombesin receptor | |||
| Bradykinin | |||
| Bradykinin receptor | |||
| Bungarotoxin | A polypeptide neurotoxin that is obtained from krait venom and yields three electrophoretic fractions of which the one designated α is used especially to label acetylcholine receptors at neuromuscular junctions because it binds irreversibly to them and blocks their activity —often used with one of the Greek prefixes α-, β-, or γ- to indicate the electrophoretic fractions. (from Merriam-Webster online dictionary) | ||
| Butyrylcholinesterase | Pseudocholinesterase Nonspecific cholinesterase Cholinesterase Pseudocholinesterase E1 Plasma Cholinesterase Choline Esterase II Butyrylcholine Esterase Acylcholine Acylhydrolase |
Human butyrylcholinesterase protein (602 aa, 68 kD), a serine esterase, is encoded by the human butyrylcholinesterase (BCHE) gene. This protein, a homotetramer, is present in most cells (except erythrocytes) and catalyzes the hydrolysis of acylcholines to yield a choline and a carboxylate anion. Reduced serum activity of the BCHE protein causes hypocholinesterasemia, a condition resulting in sensitivity to the muscle relaxant suxamethonium, which is commonly used in association with surgical anesthesia. (Definition from NCI Thesaurus and concept from MSH.) | |
| C-C Chemokine | C-C motif chemokine | ||
| C5a des Arg74 | |||
| CB1 receptor | CB1; CANN6; CB-R; CB 1; Cannabinoid receptor 1 | ||
| CB2 receptor | CB2; CB-2; CB 2; CX5; Cannabinoid receptor 2 | ||
| CCK1 receptor | CCK1; CCK-A receptor; CCK-AR; CCK1-R; Cholecystokinin-1 receptor; Cholecystokinin type A receptor | ||
| CCK2 receptor | CCK2; CCK-B receptor; CCK-BR; CCK2-R; Cholecystokinin-2 receptor; Gastrin/cholecystokinin type B receptor | ||
| CCL1 | |||
| CCL11 | eotaxin | ||
| CCL13 | |||
| CCL14 | |||
| CCL15 | |||
| CCL16 | |||
| CCL17 | |||
| CCL19 | |||
| CCL2 | |||
| CCL20 | |||
| CCL21 | |||
| CCL22 | |||
| CCL23 | |||
| CCL24 | |||
| CCL25 | |||
| CCL26 | |||
| CCL27 | |||
| CCL28 | |||
| CCL3 | |||
| CCL4 | |||
| CCL5 | |||
| CCL7 | |||
| CCL8 | |||
| CCR1 receptor | CCR1 | ||
| CCR10 receptor | CCR10 | ||
| CCR2 receptor | CCR2 | ||
| CCR3 receptor | CCR3 | ||
| CCR4 receptor | CCR4; CD184 antigen; CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor; C-X-C chemokine receptor type 4 | ||
| CCR5 receptor | CCR5; C-C CKR-5; CC-CKR-5; CCR-5; CCR 5; CD195 antigen; CHEMR13; HIV-1 fusion coreceptor; C-C chemokine receptor type 5 | ||
| CCR6 receptor | CCR6 | ||
| CCR7 receptor | CCR7 | ||
| CCR8 receptor | CCR8 | ||
| CCR9 receptor | CCR9 | ||
| CNGA1 | CNG1 CNGa1 RCNC1 |
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| CNGA2 | OCNC1 CNGa3 CNG2 |
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| CNGA3 | CNGa2 CNG3 CCNC1 |
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| CNGA4 | OCNC2 CNG5 CNGB2 CNGa4 |
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| CNGB1 | CNG4 RCNC2 CNGb1 |
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| CNGB3 | CNG6 CCNC2 CNGb2 |
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| CX3C Chemokine | |||
| CX3CL1 | |||
| CX3CR1 receptor | CX3CR1 | ||
| CXC Chemokine | |||
| CXCL1 | |||
| CXCL10 | |||
| CXCL11 | |||
| CXCL12 | |||
| CXCL13 | |||
| CXCL14 | |||
| CXCL15 | |||
| CXCL16 | |||
| CXCL2 | |||
| CXCL3 | |||
| CXCL5 | |||
| CXCL6 | |||
| CXCL7 | |||
| CXCL8 | |||
| CXCL9 | |||
| CXCR1 receptor | CXCR1 | ||
| CXCR2 receptor | CXCR2 | ||
| CXCR3 receptor | CXCR3 | ||
| CXCR4 receptor | CXCR4 | ||
| CXCR5 receptor | CXCR5 | ||
| Cadherin | A group of functionally related glycoproteins responsible for the calcium-dependent cell-to-cell adhesion mechanism. They are divided into subclasses E-, P-, and N-cadherins, which are distinct in immunological specificity and tissue distribution. They promote cell adhesion via a homophilic mechanism. These compounds play a role in the construction of tissues and of the whole animal body (MSH). | ||
| Calbindin 28K | Calbindin calbindin 1 28kDa |
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| Calcitonin | |||
| Calcitonin-gene related peptide | |||
| Calcium calmodulin protein kinase II | |||
| Calcium channel - type 1 | |||
| Calcium channel - type 2 | |||
| Calcium channel - type 3 | cacna1h | ||
| Calcium-activated potassium channel | Kca channel | ||
| Calcium-activated potassium channel - type 1 | |||
| Calcium-activated potassium channel - type 2 | |||
| Calcium-activated potassium channel - type 3 | |||
| Calcium-activated potassium channel - type 4 | IK1; IKCa1; KCa4; Putative Gardos channel; SK4 Intermediate conductance calcium-activated potassium channel protein 4, should I put under | ||
| Calcium-activated potassium channel - type 5 | |||
| Calnexin | Calnexin precursor; IP90; Major histocompatibility complex class I antigen- binding protein p88; p90 | Calnexin (CNX) is a 90kDa integral protein of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. | |
| Calpain 1 | calcium-dependent protease | ||
| Calreticulin | CRP55; Calregulin; Calreticulin precursor; ERp60; HACBP; grp60 | A multifunctional protein that is found primarily within membrane-bound organelles. In the endoplasmic reticulum it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a molecular chaperone that may play a role in protein folding or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for calcium and functions as a calcium-signaling molecule that can regulate intracellular calcium homeostasis (MSH). | |
| Calretinin | Calbindin 2 29 kDa calbindin calbindin 29K |
An intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. adapted from Entrez Gene | |
| Calsequestrin | Acidic protein found in sarcoplamic reticulum that binds calcium to the extent of 700-900 nmoles/mg. It plays the role of sequestering calcium transported to the interior of the intracellular vesicle (MSH). | ||
| Cannabinoid | |||
| Cannabinoid receptor | |||
| Carbohydrate | The largest class of organic compounds, including starches, glycogens, cellulose, gums, and simple sugars. Carbohydrates are composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n (MSH). | ||
| Carboxylic acid | |||
| CatSper1 | |||
| CatSper2 | |||
| CatSper3 | CACRC | ||
| CatSper4 | BN000273 | ||
| Catechol O-methyltransferase | Catechol Methyltransferase; Catechol-O-Methyltransferase; S-Adenosyl-L-methionine:catechol O-methyltransferase; CATECHOL METHYLTRANSFERASE O; Catechol O Methyltransferase; O-Methyltransferase Catechol; Methyltransferase Catechol |
Enzyme that catalyzes the movement of a methyl group from S-adenosylmethionone to a catechol or a catecholamine. EC 2.1.1.6. (MSH) | |
| Catecholamine | |||
| Cationic cys-loop ligand-gated ion channel | |||
| Cav alpha2 | |||
| Cav alpha2.1 | |||
| Cav alpha2.2 | |||
| Cav beta | |||
| Cav beta1 | |||
| Cav beta2 | |||
| Cav beta3 | |||
| Cav beta4 | |||
| Cav delta | |||
| Cav delta1 | |||
| Cav delta2 | |||
| Cav gamma | |||
| Cav gamma1 | |||
| Cav gamma2 | |||
| Cav gamma3 | |||
| Cav gamma4 | |||
| Cav gamma5 | |||
| Cav gamma6 | |||
| Cav gamma7 | |||
| Cav gamma8 | |||
| Cav1.1 | a1S skeletal muscle L-type Ca channel skeletal muscle dihydropyridine receptor |
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| Cav1.2 | cardiac or smooth muscle dihydropyridine receptor a1C cardiac or smooth muscle L-type Ca channel |
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| Cav1.3 | 'neuroendocrine' L-type Ca channel a1D |
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| Cav1.4 | a1F | ||
| Cav2.1 | rBA-1 (rat) BI-1 Q-type P-type a1A BI-2 (rabbit) |
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| Cav2.2 | BIII (rabbit) a1B rbB-I N-type rbB-II (rat) |
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| Cav2.3 | BII-1 rbE-II (rat) R-type BII-2 (rabbit) a1E |
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| Cav3.1 | T-type a1G CavT.1 |
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| Cav3.2 | T-type a1I |
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| Cav3.2 (nifext 2658) | CavT.2 T-type a1H |
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| Chemokine | |||
| Chemokine receptor | |||
| Chemokine receptor - unspecified 1 | |||
| Chemokine receptor - unspecified 2 | |||
| Chemokine receptor - unspecified 3 | |||
| Chemokine receptor - unspecified 4 | |||
| Cholecystokinin | |||
| Cholecystokinin receptor | |||
| Cholic | Bile acid | ||
| Choline Acetyltransferase | Choline acetylase | A synthetic enzyme that catalyzes the formation of acetylcholine from acetyl-CoA and choline. EC 2.3.1.6 (MSH). | |
| Cholinergic receptor, nicotinic, alpha 5 | CHOLINERGIC RECEPTOR NEURONAL NICOTINIC ALPHA POLYPEPTIDE 5; ACETYLCHOLINE RECEPTOR ALPHA-5 SUBUNIT Neuronal acetylcholine receptor subunit alpha-5 |
A protein that is a translation product of the CHRNA5 gene or a 1:1 ortholog thereof. Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. See MIM 118508 for additional background information on AChRs.(adapted from OMIM). | |
| Chondroitin sulfate proteoglycan | |||
| Chorionic gonadotropin | |||
| Clathrin | Major protein of the polyhedral coat of coated pits and vesicles (EMBL-EBI). | ||
| Connexin | A group of homologous proteins which form the intermembrane channels of gap junctions. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions (MSH). | ||
| Connexin 32 | |||
| Connexin 43 | A 43 kD peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a product of a gene in the alpha class of connexin genes (the alpha-1 gene). It was first isolated from mammalian heart, but is widespread in the body including the brain (MSH). | ||
| Contactin | |||
| Corticotropin releasing factor | CRF | ||
| Cortistatin | |||
| Cyan fluorescent protein | |||
| Cyclic-nucleotide gated channel | CNG channel | ||
| Cyclic-nucleotide gated channel - type A | |||
| Cyclic-nucleotide gated channel - type B | |||
| Cyclin-dependent kinase 5 | Cell division protein kinase 5 Tau protein kinase II catalytic subunit |
serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression (from Rat Genome Database) | |
| Cyclin-dependent kinase 5 regulatory subunit 1 | Tau protein kinase II 23 kDa subunit Cyclin-dependent kinase 5 activator 1 TPKII regulatory subunit CDK5 activator 1 |
A protein that serves as a neuron-specific activator of cyclin-dependent kinase 5 (CDK5)(from Entrez gene) | |
| Cys-loop ligand-gated ion channel | |||
| CysLT1 receptor | CysLT1; CysLTR1; Cysteinyl leukotriene D4 receptor; HG55; HMTMF81; LTD4 receptor; Cysteinyl leukotriene receptor 1 | ||
| CysLT2 receptor | CysLT2; CysLTR2; HG57; HPN321; hGPCR21; Cysteinyl leukotriene receptor 2 | ||
| Cystatin C | |||
| Cytidine | |||
| Cytidine 5'-diphosphate | |||
| Cytidine 5'-monophosphate | |||
| Cytidine 5'-triphosphate | |||
| Cytochrome c | A small heme protein found loosely associated with the inner membrane of the mitochondrion. | ||
| Cytoskeletal Protein | Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment points for organelles and formed bodies, and make communication between parts of the cell possible (MSH). | ||
| D1 receptor | D1; D(1A) dopamine receptor | Dopamine receptor that stimulates adenylyl cyclase activity, and has a high affinity for SKF 38393 and its homologs. D1 receptors are enriched in Caudate-putamen, nucleus accumbens, and olfactory tubercles. | |
| D2 receptor | D2; D2S; D2L; D2S/D2L; Dopamine D2 receptor; D(2) dopamine receptor | Dopamine receptor that inhibits adenylyl cyclase activity, potentiate calcium evoked release of arachadonic acid, increase potassium channel opening and in some cells decrease intracellular calcium concentrations. D2 receptors have a high affinity for antipsychotic drugs and have higher levels of expression in mammalian hippocampus and hypothalamus. | |
| D3 receptor | D3; D(3) dopamine receptor | Dopaminergic receptor that decreases adenylyl cyclase activity and is enriched in the Islands of Calleja, olfactory tubercles, and the nucleus accumbens. | |
| D4 receptor | D4; D(2C) dopamine receptor; Dopamine D4 receptor; D(4) dopamine receptor | Dopaminergic receptor that decreases adenylyl cyclase activity and is enriched in expression in the frontal cortex, diencephalon, and the brain stem. | |
| D5 receptor | D5; 1B; D(5) dopamine receptor; D1beta dopamine receptor; D(1B) dopamine receptor | Dopaminergic receptor that stimulates adenylyl cyclase activity and is found primarily in the hippocampus and hypothalamus. | |
| DNA | Deoxyribonucleic acid | A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine) (MSH). | |
| DOPA | |||
| DOPA decarboxylase | Aromatic L-amino acid decarboxylase; DOPA-decarboxylase; EC 4.1.1.28 | Synthetic enzyme for Dopamine from DOPA, involves the cofactor Pyridoxal phosphate. | |
| DP receptor | DP; PGD receptor; Prostanoid DP receptor; Prostaglandin D2 receptor | ||
| Delta receptor | delta opioid receptor; DOR-1; Delta-type opioid receptor | ||
| DeltaFosB | Delta FosB ΔFosB |
||
| Deoxycytidine | |||
| Deoxyguanosine | |||
| Dimeric dimer ion channel | |||
| Dimeric ion channel | |||
| Dopamine Transporter Type 1 | Sodium dependent transport protein, located on presynaptic terminals, involved in the uptake of dopamine; site at which cocaine exerts rewarding/ reinforcing effects (CSP). | ||
| Dopamine beta-hydroxylase | Dopamine beta-Monooxygenase; 3 4-Dihydroxyphenethylamine ascorbate:oxygen oxidoreductase (beta-hydroxylating); Dopamine beta Hydroxylase; beta-Hydroxylase Dopamine; Dopamine beta Monooxygenase; beta-Monooxygenase Dopamine; Dopamine beta Monooxygenase; 3 ascorbate:oxygen oxidoreductase (beta-hydroxylating); Dopamine beta-Monooxygenase |
Catalysis of the reaction: 3,4-dihydroxyphenethylamine + ascorbate + O2 = noradrenaline + dehydroascorbate + H2O. (Cu2+ is cofactor) (adapted from GO) | |
| Dopamine receptor | DA DA receptor |
Receptor that binds dopamine. These receptors are either D1-like receptors or D2-like receptors, where the D1 receptors (D1 and D5) increase adenylyl cyclase activity and the D2-like receptors (D2, D3, and D4) decrease adenylyl cyclase activity. The two families are distinguishable by expression patterns and pharmacology, and involved with different disease states. D1-like receptor family is involved with the brain's reward system and schizophrenia, while D2-like family is involved with motor control systems and Parkinsons disease. | |
| Dopamine transporter | Dopamine active transporter | ||
| Doublecortin | A cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex (Entrez Gene definition: GeneID: 1641. | ||
| Drebrin | |||
| Dynamin | A family of high molecular weight GTP phosphohydrolases that play a direct role in vesicle transport. They associate with microtubule bundles (microtubules) and are believed to produce mechanical force via a process linked to GTP hydrolysis (MSH). | ||
| Dynorphin | |||
| Dynorphin A | |||
| EAAT1 | |||
| EAAT2 | |||
| EAAT3 | |||
| EAAT4 | |||
| EP1 receptor | EP1; PGE receptor EP1 subtype; Prostanoid EP1 receptor; Prostaglandin E2 receptor EP1 subtype |
||
| EP2 receptor | EP2; PGE receptor EP2 subtype; Prostanoid EP2 receptor; Prostaglandin E2 receptor EP2 subtype |
||
| EP3 receptor | EP3; PGE receptor EP3 subtype; PGE2-R; Prostanoid EP3 receptor; Prostaglandin E2 receptor EP3 subtype |
||
| EP4 receptor | EP4; PGE receptor EP4 subtype; Prostanoid EP4 receptor; Prostaglandin E2 receptor EP4 subtype |
||
| ERK | Extracellular signal-related protein kinase | ||
| ERp57 | |||
| ETA receptor | ETA; ET-A; ETA-R; Endothelin A receptor; Endothelin-1 receptor precursor; hET- AR; Endothelin-1 receptor | ||
| ETB receptor | ETB; ET-B; Endothelin B receptor precursor; Endothelin receptor Non- selective type; Endothelin B receptor | ||
| Eicosanoid lipid | |||
| Endoplasmin | |||
| Endorphin | |||
| Endothelin | |||
| Endothelin 1 | |||
| Endothelin 2 | |||
| Endothelin 3 | |||
| Endothelin receptor | |||
| Enhanced green fluorescent protein | Variation of the green fluorescent protein with a point mutantion with enhanced fluorescent yield relative to wild type GFP | ||
| Enkephalin | |||
| ErkA | ERK1 | ||
| ErkB | ERK2 | ||
| Estrogen | |||
| F-actin | |||
| FFA1 receptor | FFA1; G-protein coupled receptor 40; Free fatty acid receptor 1 | ||
| FFA2 receptor | FFA2 | ||
| FFA3 receptor | FFA3 | ||
| FOS | FOS protein | A class of nuclear leucine zipper proteins (FOS, FOSB, FOSL1, and FOSL2) that can dimerize with JUN Family proteins and bind DNA as the AP-1 transcription factor complex to regulate transcription in cell proliferation, differentiation. | |
| FP receptor | FP; PGF receptor; PGF2 alpha receptor; Prostanoid FP receptor; Prostaglandin F2-alpha receptor | ||
| FSH receptor | FSH | ||
| Fatty acid | long chain carboxylic acid | ||
| Fluorescent protein | Protein that possesses native fluorescence. Naturally occuring fluorescent proteins include green fluroescent protein, originally isolated from the jellyfish. Other colors of fluorescent proteins were produced through mutations, e.g., the Yellow fluorescent protein. These proteins are used extensively as biosensors through fusion of gene for the fluorescent protein to a target protein. | ||
| Follicle-stimulating hormone | |||
| FosB | |||
| Fragile X mental retardation protein | Protein FMR-1SYNCI | Fragile X mental retardation 1 protein (632 aa, ~71 kDa) is encoded by the human FMR1 gene. This protein may be involved in mRNA transport. From NCI Thesaurus. | |
| Free fatty acid receptor | |||
| Free fatty acid receptor - unspecified 1 | |||
| G protein-coupled bile acid receptor | |||
| G-Protein | |||
| G-actin | |||
| G-betagamma | G?? beta-gamma complex |
||
| G-protein coupled receptor | 7TM membrane receptor | test | |
| GABA | Gamma-Aminobutyric acid | Amino acid that serves as the major inhibitory neurotransmitter in the mammalian central nervous system. | |
| GABA A-gated anionic channel | GABA A receptor GABAA GABAA R |
GABA-activated chloride channel (anionic) expressed throughout the vertebrate central nervous system, that is modified by many drugs including: GABA; Picrotoxin, convulsants and depressants; barbituates; steroids, volitile compounds and anesthetics; and benzodiazapines and ethanol. | |
| GABA C-gated anionic channel | GABA C receptor GABAC GABA(C) GABA-C |
An anionic channel, permeable to chloride, that is insensitive to bicuculline and baclofen, but sensitive to GABA and its analogs, including cis-4-aminocrotonic acid (CACA). | |
| GABA-B Receptor | GABAB GABA B Receptor GABA_B Gamma-aminobutyric acid-B receptor |
Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and influence cells via interactions with G-proteins. GABA-B receptors are pharmacologically characterized by their insensitivity to the blocker bicuculline and sensitivity to the agonist L-baclofen. They are found both presynaptically and postsynaptically, and act variously by inhibition of adenylate cyclase, activation of phospholipase A2, activation of potassium channels, and inactivation of voltage-activated calcium channels. Year introduced: 1994 - definition from MeSH | |
| GABA-gated anionic channel | GABA receptor | ||
| GABBR1 | GABA-B receptor 1; GABA-B-R1; Gamma-aminobutyric acid type B receptor subunit precursor; Gb1; Gamma-aminobutyric acid type B receptor subunit 1; GAMMA-AMINOBUTYRIC ACID B RECEPTOR 1; GABA-B RECEPTOR R1 SUBUNIT; GABABR1 |
taken from OMIM | |
| GABBR2 | G-protein coupled receptor 51; GABA-B receptor 2; GABA-B-R2; GABABR2; Gamma-aminobutyric acid type B receptor subunit 2 precursor; Gb2; HG20; Gamma-aminobutyric acid type B receptor subunit 2; GAMMA-AMINOBUTYRIC ACID B RECEPTOR 2; GABA-B RECEPTOR R2 SUBUNIT; GABABR2; GPR51 |
taken from OMIM | |
| GABRA1 | GABA-A RECEPTOR; ALPHA-1 POLYPEPTIDE ; GABRA1; Gamma-aminobutyric-acid receptor subunit alpha-precursor; Gamma-aminobutyric-acid receptor subunit alpha-1 | taken from OMIM | |
| GABRA2 | GABA(A) receptor subunit alpha-2; Gamma-aminobutyric-acid receptor subunit alpha-2 precursor; Gamma-aminobutyric-acid receptor subunit alpha-2; GABA-A RECEPTOR ALPHA-2 POLYPEPTIDE; GAMMA-AMINOBUTYRIC ACID RECEPTOR ALPHA-2 |
taken from OMIM | |
| GABRA3 | GAMMA-AMINOBUTYRIC ACID RECEPTOR ALPHA-3; GABA-A RECEPTOR ALPHA-3 POLYPEPTIDE; Gamma-aminobutyric-acid receptor subunit alpha-3 precursor; Gamma-aminobutyric-acid receptor subunit alpha-3 |
taken from OMIM | |
| GABRA4 | Gamma-aminobutyric-acid receptor subunit alpha-4 precursor; Gamma-aminobutyric-acid receptor subunit alpha-4; GAMMA-AMINOBUTYRIC ACID RECEPTOR ALPHA-4; GABA-A RECEPTOR ALPHA-4 POLYPEPTIDE; |
taken from OMIM | |
| GABRA5 | Gamma-aminobutyric-acid receptor subunit alpha-5 precursor; Gamma-aminobutyric-acid receptor subunit alpha-5; GAMMA-AMINOBUTYRIC ACID RECEPTOR ALPHA-5; GABA-A RECEPTOR ALPHA-5 POLYPEPTIDE; |
taken from OMIM | |
| GABRA6 | Gamma-aminobutyric-acid receptor subunit alpha-6 precursor; Gamma-aminobutyric-acid receptor subunit alpha-6; GAMMA-AMINOBUTYRIC ACID RECEPTOR ALPHA-6; GABA-A RECEPTOR ALPHA-6 POLYPEPTIDE |
taken from OMIM | |
| GABRB1 | GABA(A; Gamma-aminobutyric-acid receptor subunit beta-precursor; Gamma-aminobutyric-acid receptor subunit beta-1; GAMMA-AMINOBUTYRIC ACID RECEPTOR BETA-1; GABA-A RECEPTOR BETA-1 POLYPEPTIDE |
taken from OMIM | |
| GABRB2 | GABA(A; Gamma-aminobutyric-acid receptor subunit beta-2 precursor; Gamma-aminobutyric-acid receptor subunit beta-2; GAMMA-AMINOBUTYRIC ACID RECEPTOR BETA-2; GABA-A RECEPTOR BETA-2 POLYPEPTIDE |
taken from OMIM | |
| GABRB3 | GABA(A; Gamma-aminobutyric-acid receptor subunit beta-3 precursor; Gamma-aminobutyric-acid receptor subunit beta-3; GAMMA-AMINOBUTYRIC ACID RECEPTOR BETA-3; GABA-A RECEPTOR BETA-3 POLYPEPTIDE |
taken from OMIM | |
| GAD67 | Glutamate decarboxylase 67 kDa isoform 67 kDa glutamic acid decarboxylase GAD-67 glutamic acid decarboxylase 1 |
An enzyme that catalyzes the production of gamma-aminobutyric acid from L-glutamic acid. | |
| GAL1 receptor | GAL1 | ||
| GAL2 receptor | GAL2 | ||
| GAL3 receptor | GAL3 | ||
| GPBA receptor | GPBA | ||
| Galanin | |||
| Galanin receptor | |||
| Gamma secretase | A protein complex containing presenilin, nicastrin, ACH-1, and PEN-2. Presenilin is believed to harbor the protease domain and represents an important example of an uncommon type of protease that cleaves targets within the cell membrane. | ||
| Gamma-Synuclein Protein | BCSG1 Breast Cancer-specific Gene Persyn |
A synuclein protein found primarily in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. It is also detected in the brain, ovarian tumors, breast tumors, and in the olfactory epithelium. It is the least conserved of the synuclein proteins. | |
| Gamma-melanocyte stimulating hormone | g-melanocyte stimulating hormone gamma-MSH |
||
| Ganglioside | |||
| Gastric inhibitory polypeptide | |||
| Gastrin | |||
| Gastrin-releasing peptide | |||
| Ghrelin | |||
| Ghrelin receptor | ghrelin | ||
| Gi | G-protein i | ||
| Glial Fibrillary Acidic Protein | The major component of glia-specific intermediate filament primarily found in astrocytes and Bergmann glia. | ||
| Glial cell derived neurotrophic factor | A small protein that potently promotes the survival of many types of neurons (adapted from Wikipedia) | ||
| GluCl glutamate-gated chloride channel | GluCl glutamate receptor; Avermectin- sensitive glutamate-gated chloride channel subunit; Glu-Cl beta subunit; Glutamate-gated chloride channel subunit beta precursor; Glutamate-gated chloride channel subunit beta | ||
| GluR1 | |||
| GluR2 | gria2 dkfzp459f083 glur2 glur-2 glur-b glur-k2 mgc139795 glurb hbgr2 |
||
| GluR3 | |||
| Glucocorticoid | A steroid hormone that regulates a variety of physiological processes, in particular control of the concentration of glucose in blood. | ||
| Glucose | |||
| Glutamate | Glut | The carboxylate anion of glutamic acid; and the major excitatory neurotransmitter in the central nervous system of vertebrates, the peripheral nervous system of invertebrates. | |
| Glutamate Transporter | Excitatory Amino Acid Transporters EAAT |
||
| Glutamate decarboxylase 2 | Enzyme responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid with a molecular weight of 65 kDa. | ||
| Glutamate-gated cationic channel | Glutamate receptor GluR |
Cell-surface proteins that bind glutamate and trigger changes which influence the behavior of cells. Glutamate receptors include ionotropic receptors (AMPA, kainate, and N-methyl-D-aspartate receptors), which directly control ion channels, and metabotropic receptors which act through second messenger systems. Glutamate receptors are the most common mediators of fast excitatory synaptic transmission in the central nervous system. They have also been implicated in the mechanisms of memory and of many diseases (MSH). | |
| Glutamic acid decarboxylase | |||
| Glycine-gated chloride channel | Glycine receptor; GABA-gated chloride channel subunit | ||
| Glycogen | |||
| Glycogen synthase kinase-3 alpha | a multifunctional protein serine kinase, homologous to Drosophila 'shaggy' (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase (from NCBI Entrez Gene) | ||
| Glycogen synthase kinase-3 beta | A serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (NCBI Entrez Gene) | ||
| Glycoprotein | A compound in which a carbohydrate component is covalently bound to a protein component.(CHEBI) | ||
| Glycoprotein hormone receptor | |||
| GnRH receptor | |||
| GnRH receptor - unspecified 1 | |||
| GnRH receptor - unspecified 2 | GnRH-II-R; Type II GnRH receptor; Gonadotropin-releasing hormone II receptor | ||
| Gonadotrophin-releasing hormone | gonadorelin; Gonadotropin-releasing hormone; Luteinizing-hormone releasing hormone; GnRH receptor; GnRH-R; Gonadotropin-releasing hormone receptor | ||
| Gq | Gq/11 | ||
| Green fluorescent protein | A naturally occuring fluorescent protein of 238 amino acids (26.9 kDa), originally isolated from the jellyfish Aequorea victoria that fluoresces green when exposed to blue light. The GFP from A. victoria has a major excitation peak at a wavelength of 395 nm and a minor one at 475 nm. Its emission peak is at 509 nm which is in the lower green portion of the visible spectrum. The GFP from the sea pansy (Renilla reniformis) has a single major excitation peak at 498 nm. In cell and molecular biology, the GFP gene is frequently used as a reporter of expression. In modified forms it has been used to make biosensors, and many animals have been created that express GFP as a proof-of-concept that a gene can be expressed throughout a given organism. (Adapted from Wikipedia) | ||
| Growth hormone-releasing hormone | |||
| Gs | G-protein s | ||
| Guanosine | |||
| Guanosine 3',5'-cyclic monophosphate | |||
| Guanosine 5'-diphosphate | |||
| Guanosine 5'-monophosphate | |||
| Guanosine 5'-triphosphate | |||
| H1 receptor | H1; Histamine H1 receptor | ||
| H2 receptor | H2; Gastric receptor I; H2R; Histamine H2 receptor | ||
| H3 receptor | H3; G-protein coupled receptor 97; HH3R; Histamine H3 receptor | ||
| H4 receptor | H4; AXOR35; G-protein coupled receptor 105; GPCR105; GPRv53; HH4R; SP9144; Histamine H4 receptor | ||
| HCN1 | HAC2 BCNG1 |
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| HCN2 | BCNG2 HAC1 |
||
| HCN3 | HAC3 BCNG4 |
||
| HCN4 | BCNG3 HAC4 |
||
| Heterotrimeric G proteins | G12/13 | ||
| Histamine | is produced by basophils and mast cells (in connective tissues) and is involved in local immune responses and regulating physiological function in the gut and acting as a neurotransmitter. - adapted from Wikipedia | ||
| Histamine receptor | |||
| Histamine-gated chloride channel | |||
| Horse radish peroxidase | Horseradish peroxidase | An enzyme found in horseradish that is used extensively in molecular biology applications primarily for its ability to amplify a weak signal and increase detectability of a target molecule | |
| Huntingtin | is the protein coded by the gene, huntingtin, identified in 1993. It is variable in its structure as there are many polymorphisms of the gene which can lead to variable numbers of glutamine residues present in the protein. In its wild-type form, it contains 6-35 glutamine residues; however, in individuals affected by Huntington's Disease, it contains more than 36 glutamine residues. Huntingtin has a predicted mass of ~350kDa, although this varies and is largely dependent on the number of glutamine residues in the protein. Normal huntingtin is generally accepted to be 3144 amino acids in size. Adapted from Wikipedia | ||
| Hyperpolarization and cyclic-nucleotide gated channel | HCN channel | ||
| IP1 receptor | IP1; PGI receptor; Prostaglandin I2 receptor; Prostanoid IP receptor Prostacyclin receptor | ||
| Insulin | A hormone composed of 51 amino acids and has a molecular weight of 5808 Da. It is produced in the islets of Langerhans in the pancreas. | ||
| Insulin like growth factor 1 | |||
| Insulin-like peptide | |||
| Insulin-like peptide 5 | |||
| Integrin | |||
| Interleukin | A group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes), The term interleukine, (inter-) as a means of communication, (-leukin) deriving from the fact that many of these proteins are produced by leukocytes and act on leukocytes. The name is something of a relic though (the term was coined by Dr. Paetkau, University of Victoria); it has since been found that interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. (Adapted from Wikipedia) | ||
| Interleukin-1 | A soluble factor produced by monocytes, macrophages, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the same functions but are distinct proteins. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation. The factor is distinct from INTERLEUKIN-2 (MSH). | ||
| Inwardly rectifying potassium channel | Kir channel | ||
| Inwardly rectifying potassium channel - type 1 | |||
| Inwardly rectifying potassium channel - type 2 | |||
| Inwardly rectifying potassium channel - type 3 | |||
| Inwardly rectifying potassium channel - type 4 | |||
| Inwardly rectifying potassium channel - type 5 | |||
| Inwardly rectifying potassium channel - type 6 | |||
| Inwardly rectifying potassium channel - type 7 | |||
| K2p1.1 | TWIK-1 hONO KCNK1 |
||
| K2p10.1 | TREK-2 KCNK10 |
||
| K2p12.1 | THIK-2 KCNK12 |
||
| K2p13.1 | KCNK13 THIK-1 |
||
| K2p15.1 | TASK-5 KCNK15 KT3.3 |
||
| K2p16.1 | TALK-1 KCNK16 |
||
| K2p17.1 | KCNK17 TALK-2 TASK-4 |
||
| K2p18.1 | TRIK | ||
| K2p2.1 | KCNK2 TPKC1 TREK-1 |
||
| K2p3.1 | TASK-1 KCNK3 TBAK-1 OAT-1 |
||
| K2p4.1 | KCNK4 TRAAK |
||
| K2p5.1 | TASK-2 KCNK5 |
||
| K2p6.1 | TWIK-2 KCNK6 TOSS |
||
| K2p7.1 | KCNK7 kcnk8 |
||
| K2p9.1 | KCNK9 TASK-3 |
||
| KCa beta | |||
| KCa beta1 | |||
| KCa beta2 | |||
| KCa beta3 | |||
| KCa beta4 | |||
| KIF3A | |||
| Kainate glutamate-gated cationic channel | Kainate receptor | ||
| Kappa receptor | kappa; KOR-1; Kappa-type opioid receptor | ||
| Katanin | Katanin complex | A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa). | |
| Kca1.1 | KCNMA1; Slo; maxi K+ channel; BK channel;BKCA alpha; Calcium-activated potassium channel subfamily M subunit alpha 1; K(VCA)alpha; KCa1.1; Maxi K channel; MaxiK; Slo homolog; Slo-alpha; Slo1; Slowpoke homolog; hSlo; Calcium-activated potassium channel subunit alpha 1 |
||
| Kca2.1 | KCNN1 SKCa1 SK1 |
||
| Kca2.2 | SKCa2 KCNN2 SK2 |
||
| Kca2.3 | KCNN3 SK3 hKCa3 SKCa3 |
||
| Kca3.1 | KCNN4 SK4 IK1 Gardos channel IKCa1 KCa4 |
||
| Kca4.1 | mSlo2 Slack |
||
| Kca4.2 | |||
| Kca5.1 | Slo3 KCNMC1 |
||
| KiSS-1 gene product | |||
| KiSS1 receptor | KiSS1 | ||
| KiSS1-derived peptide receptor | |||
| Kir1.1 | ROMK1; ATP-regulated potassium channel ROM-K; Kir1.1; Potassium channel inwardly rectifying subfamily J member 1; ATP-sensitive inward rectifier potassium channel 1 |
||
| Kir2.1 | IRK1 | ||
| Kir2.2 | IRK2; IRK2; Inward rectifier K(+) channel Kir2.2v; Kir2.2v; Potassium channel inwardly rectifying subfamily J member 12; ATP-sensitive inward rectifier potassium channel 12 |
||
| Kir2.3 | hIRK2 IRK3 HIR HRK1 |
||
| Kir2.4 | IRK4 | ||
| Kir3.1 | KGA GIRK1; GIRK1; Inward rectifier K(+) channel Kir3.1; Potassium channel inwardly rectifying subfamily J member 3; G protein-activated inward rectifier potassium channel 1 |
||
| Kir3.2 | GIRK2; BIR1; GIRK2; Inward rectifier K(+) channel Kir3.2; KATP-2; Potassium channel inwardly rectifying subfamily J member 6; G protein-activated inward rectifier potassium channel 2 |
||
| Kir3.3 | GIRK3 | ||
| Kir3.4 | GIRK4 | ||
| Kir4.1 | BIR10 KAB-2 Kir1.2 |
||
| Kir4.2 | Kir1.3 ROMK3 |
||
| Kir5.1 | |||
| Kir6.1 | uKATP-1; Inwardly rectifier K(+) channel Kir6.1; Potassium channel inwardly rectifying subfamily J member 8; uKATP-1; ATP-sensitive inward rectifier potassium channel 8 |
||
| Kir6.2 | BIR; IKATP; Inward rectifier K(+) channel Kir6.2; Potassium channel inwardly rectifying subfamily J member 11; ATP-sensitive inward rectifier potassium channel 11 |
||
| Kir7.1 | |||
| Kv beta | |||
| Kv beta1 | |||
| Kv beta2 | |||
| Kv beta3 | |||
| Kv1.1 | MBK1 MK1 HBK1 RBK1 RCK1 HuK(I) |
||
| Kv1.2 | HuK(IV) NGK1 RAK MK2 HBK5 RCK5 BGK5 XSha2 BK2 |
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| Kv1.3 | MBK3 MK3 hPCN3 HGK5 RGK5 RCK3 HLK3 HuK(III) KV3 |
||
| Kv1.4 | HK1 HuK(II) RCK4 RHK1 hPCN2 RK8 MK4 RK4 |
||
| Kv1.5 | HK2 RMK2 HuK(II) HCK1 hPCN1 fHK KV1 RK3 |
||
| Kv1.6 | KCNA6 KV2 HBK2 RCK2 MK1.6 |
||
| Kv1.7 | KCNA7 | ||
| Kv1.8 | KCNA10 Kv1.10 Kcn1 |
||
| Kv10.1 | ether-a-go-go KCNH1b eag1a KCNH1a eag1b |
||
| Kv10.2 | eag2 KCNH5 |
||
| Kv11.1 | KCNH2 HERG erg1 Hergb human ether-a-go-go-related gene |
||
| Kv11.2 | erg2 | ||
| Kv11.3 | erg3 | ||
| Kv12.1 | elk1 elk3 |
||
| Kv12.2 | BEC1 KCNH3 Elk2 |
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| Kv12.3 | elk1 BEC2 KCNH4 |
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| Kv2.1 | DRK1 hDRK1 |
||
| Kv2.2 | CDRK KCNB2 |
||
| Kv3.1 | NGK2 Kv3.1 type I channel in T cells KV4 Raw2 |
||
| Kv3.2 | rKv3.2b rKv3.2c Kv3.2a RKShIIIA Raw1 |
||
| Kv3.3 | Kv3.3b hKv3.3 mKv3.3 RKShIIID |
||
| Kv3.4 | HKShIIIC mKv3.4 Raw3 |
||
| Kv4.1 | mShal | ||
| Kv4.2 | RK5 Shal1 |
||
| Kv4.3 | |||
| Kv5.1 | IK8 KH1 KCNF1 |
||
| Kv6.1 | K13 KH2 |
||
| Kv6.2 | KCNG2 | ||
| Kv6.3 | KCNG3 Kv10.1 |
||
| Kv6.4 | |||
| Kv7.1 | KVLQT1 slow delayed rectifier |
||
| Kv7.2 | KQT2 KCNQ2 |
||
| Kv7.3 | KCNQ3 | ||
| Kv7.4 | KCNQ4 | ||
| Kv7.5 | KCNQ5 | ||
| Kv8.1 | Kv2.3 HNKA |
||
| Kv8.2 | |||
| Kv9.1 | |||
| Kv9.2 | |||
| Kv9.3 | |||
| L dopa | L-DOPA levodopa |
The levorotatory enantiomer of DOPA | The preferred label for this should be capitalized: L DOPA |
| L1 | Cell adhesion molecule expressed at neuronal surface. | ||
| LH receptor | LH; LH/CG-R; LHR; LSH- R; Luteinizing hormone receptor; Lutropin-choriogonadotropic hormone receptor precursor; Lutropin-choriogonadotropic hormone receptor | ||
| LPA1 receptor | LPA1 | ||
| LPA2 receptor | LPA2 | ||
| LPA3 receptor | LPA3 | ||
| LPC receptor | |||
| LPC receptor - unspecified 1 | |||
| LPC receptor - unspecified 2 | |||
| LPC receptor - unspecified 3 | |||
| LPC receptor - unspecified 4 | |||
| Laminin complex | Laminin | A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes. | |
| Lectin | |||
| Leptin | A protein hormone secreted by adipocytes involved in the regulation of body fat stores. The human form is ~167 aa, ~16 kD encoded by the leptin gene (LEP). (adapted from Wikipedia) | I'm classifying this as a protein rather than a peptide because it is ~160 aa in length. At least one definition of a peptide is that it is less than 50 aa, but as I understand it, this definition is somewhat arbitrary. We may want to drop the peptide/protein distinction and go with peptide or polypeptide or something like that. | |
| Leu enkephalin | leucine enkephalin | One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN (MeSH) | |
| Leukotriene | |||
| Leukotriene B4 | |||
| Leukotriene C4 | |||
| Leukotriene D4 | |||
| Leukotriene and lipoxin receptor | |||
| Lipid | A substances of biological origin that is soluble in nonpolar solvents, consisting of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids (adapted from CHEBI). | ||
| Lipopolysaccharide | Natural compound consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). | ||
| Lipoprotein | A clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids. | ||
| Lipoxin | |||
| Lipoxin A | |||
| Lipoxin A4 | |||
| Lipoxin B | |||
| Lipoxin B4 | |||
| Luteinizing hormone | |||
| Lysophosphatidic acid | |||
| Lysophospholipid | |||
| Lysophospholipid receptor | |||
| Lysosome associated membrane protein | lysosomal integral membrane protein | ||
| M1 receptor | M1 M1 AChR M1 acetylcholine receptor Muscarinic acetylcholine receptor M1 |
A specific subtype of muscarinic receptor that has a high affinity for the drug PIRENZEPINE. It is found in the peripheral GANGLIA where it signals a variety of physiological functions such as GASTRIC ACID secretion and BRONCHOCONSTRICTION. This subtype of muscarinic receptor is also found in neuronal tissues including the CEREBRAL CORTEX and HIPPOCAMPUS where it mediates the process of MEMORY and LEARNING. Year introduced: 2004 - adapted from MeSH | |
| M2 receptor | M2 M2 AChR M2 acetylcholine receptor Muscarinic acetylcholine receptor M2 |
A specific subtype of muscarinic receptor found in the lower BRAIN, the HEART and in SMOOTH MUSCLE-containing organs. Although present in smooth muscle the M2 muscarinic receptor appears not to be involved in contractile responses. Year introduced: 2004 - adapted from MeSH | |
| M3 receptor | M3 M3 Acetylcholine receptor M3 AChR Muscarinic acetylcholine receptor M3 |
A subclass of muscarinic receptor that mediates cholinergic-induced contraction in a variety of SMOOTH MUSCLES. Year introduced: 2004 - Adapted from MeSH | |
| M4 receptor | M4 M4 Acetylcholine receptor M4 AChR; Muscarinic acetylcholine receptor M4 |
A specific subtype of muscarinic receptor found in the CORPUS STRIATUM and the LUNG. It has similar receptor binding specificities to MUSCARINIC RECEPTOR M1 and MUSCARINIC RECEPTOR M2. Year introduced: 2004 - Adapted from MeSH | |
| M5 receptor | M5 M5 Acetylcholine receptor M5 AChR Muscarinic acetylcholine receptor M5 |
A specific subtype of muscarinic receptor found in a variety of locations including the SALIVARY GLANDS and the SUBSTANTIA NIGRA and VENTRAL TEGMENTAL AREA of the BRAIN. Year introduced: 2004 - Adapted from MeSH | |
| MAO | MAO-B; Amine:oxygen oxidoreductase (deaminating) (flavin-containing); Oxidase Monoamine; Oxidase Tyramine; MAO A; MAO B; Type A Monoamine Oxidase; Monoamine Oxidase B; Amine Oxidase (Flavin-Containing); MAO; Tyramine Oxidase; Monoamine Oxidase A; MAO-A; Type B Monoamine Oxidase; Monoamine Oxidase |
An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4. (from MSH) | |
| MAP kinase | mitogen activated protein kinase mitogen-activated protein kinase |
||
| MAP1 | Microtubule-associated protein 1 | ||
| MAP1A | Microtubule associated protein 1A | ||
| MAP1B | Microtubule-associated protein 1B | ||
| MAP2 | Microtubule associated protein 2 | ||
| MAP5 | A microtubule-associated protein that appears to be evenly distributed throughout axons, dendrites, and neuronal cell bodies. It is absent in synapses, which make it distinguishable from other MAPs (1, 2, 3, and tau). It is not present in dendritic spines, axon terminals, or other synaptic elements. It is present at significantly higher levels in neonatal brain than adult. | ||
| MC1 receptor | MC1 | ||
| MC2 receptor | MC2; ACTH receptor; ACTH-R; Adrenocorticotropin receptor; MC2-R; Melanocortin receptor 2; Adrenocorticotropic hormone receptor | ||
| MC3 receptor | MC3 | ||
| MC4 receptor | MC4 | ||
| MC5 receptor | MC5 | ||
| MCH1 receptor | MCH1 | ||
| MCH2 receptor | MCH2 | ||
| MGluR1 | Metabotropic glutamate receptor 1 GRM1 Glutamate metabotropic receptor 1 metabotropic glutamate 1 Metabotropic glutamate receptor 1 precursor |
Group I metabotropic glutamate receptor, positively coupled to phospholipid metabolism. | |
| MGluR2 | GRM2 Metabotropic glutamate receptor 2 Glutamate metabotropic receptor 2 Glutamate metabotropic 2 Metabotropic glutamate receptor 2 precursor |
Group II glutamate receptor negatively coupled to adenylyl cyclase. | |
| MGluR3 | Metabotropic glutamate receptor 3 GRM3 Glutamate metabotropic receptor 3 Glutamate metabotropic 3 Metabotropic glutamate receptor 3 precursor |
Group II metabotropic glutamate receptor, negatively coupled to adenylyl cyclase. | |
| MGluR4 | GRM4 Metabotropic glutamate receptor 4 Glutamate metabotropic receptor 4 Glutamate metabotropic 4 Metabotropic glutamate receptor 4 precursor |
Group III metabotropic glutamate receptor, negatively coupled to adenylyl cyclase activity. | note there is a subcategory for this that should be deleted. It is the same as the supercategory. |
| MGluR5 | GRM5 Metabotropic glutamate receptor 5 Glutamate metabotropic receptor 5 Glutamate metabotropic 5 Metabotropic glutamate receptor 5 precursor mGlu5 5 metabotropic glutamate receptor |
Group I metabotropic glutamate receptor, positively coupled to phospholipid metabolism. | |
| MGluR5a | Metabotropic glutamate receptor 5a Glutamate metabotropic receptor 5a Glutamate metabotropic 5a |
Group I metabotropic glutamate receptor, positively coupled to phospholipid metabolism and found in the retina. | |
| MGluR6 | GRM6 Metabotropic glutamate receptor 6 Glutamate metabotropic receptor 6 Glutamate metabotropic 6 |
Group III metabotropic glutamate receptor, negatively coupled to adenylyl cyclase. | |
| MGluR7 | Metabotropic glutamate receptor 7 GRM7 Glutamate metabotropic receptor 7 Glutamate metabotropic 7 Metabotropic glutamate receptor 7 precursor |
Group III metabotropic glutamate receptor, negatively coupled to adenylyl cyclase. | |
| MGluR8 | GRM8 Metabotropic glutamate receptor 8 Glutamate metabotropic receptor 8 Glutamate metabotropic 8 Metabotropic glutamate receptor 8 precursor |
Group III metabotropic glutamate receptor, negatively coupled to adenylyl cyclase. | |
| MRNA | RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm (MSH). | ||
| MT1 receptor | MT1; Mel-1A-R; Mel1a melatonin receptor; Melatonin receptor type 1A; Mel-1B-R; Mel1b melatonin receptor; Melatonin receptor type 1B | ||
| MT2 receptor | MT2 | ||
| Macromolecular complex | |||
| Macromolecule | |||
| Macrophage derived lectin | |||
| Melanin-concentrating hormone | |||
| Melanin-concentrating hormone receptor | |||
| Melanocortin receptor | |||
| Melanocyte stimulating hormone | |||
| Melatonin receptor | |||
| Met enkephalin | methionine enkephalin | One of the endogenous pentapeptides with morphine-like activity. It differs from LEU-ENKEPHALIN by the amino acid METHIONINE in position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN (MeSH) | |
| Metabotropic Glutamate Receptor | mGluRs GRM Glutamate metabotropic Metabotropic glutamate |
The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor which are active through an indirect metabotropic process. They are members of the group C family of G-protein-coupled receptors, or GPCRs, and are divided into 3 groups based on sequence homology and binding affinities. Like all glutamate receptors, mGluRs bind to glutamate, an amino acid that functions as an excitatory neurotransmitter.
Group I mGluR's are coupled to phospholipid metabolism and comprise members 1 and 5 Group II mGluR's are coupled to reduced cAMP turnover and comprise members 2, 3 and 4 Group III mGluR's are coupled to reduced cAMP turnover and comprise members 6, 7, and 8 |
|
| MinK-like | |||
| MinK-like 1 | |||
| MinK-like 2 | |||
| MinK-like 3 | |||
| MinK-like 4 | |||
| MinK-like 5 | |||
| Mitochondrial DNA | Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial genome is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins (MSH). | ||
| Monoamines | |||
| Monoclonal antibody | Monoclonal Monoclonal antibodies |
||
| Monomeric Voltage-gated ion channel | |||
| Monomeric ion channel | |||
| Motilin | |||
| Motilin receptor | motilin | ||
| Mu receptor | mu; MOR-1 Mu-type opioid receptor |
||
| Multimeric Voltage-gated ion channel | Voltage-gated ion channel | ||
| Multimeric ion channel | |||
| Myelin Basic Protein | A group of 7 proteins produced from a single gene by alternate splicing found in central and peripheral nervous system myelin. The major basic protein (MBP) has long been of interest because it is the antigen, that, when injected into an animal, elicits a cellular immune response that produces the CNS autoimmune disease called experimental allergic encephalomyelitis (encephalomyelitis, allergic). In the peripheral nervous system, myelin basic protein 18.5 kD is often referred to as the P1 protein. (From Siegel et al., Basic Neurochemistry, 5th ed, p130, 133) (MSH) | ||
| Myosin | A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyse MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are are involve in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain (MSH). | ||
| N-formyl-L-Met-L-Leu-L-Phe | |||
| N-formylpeptide receptor | |||
| N-formylpeptide receptor - unspecified 1 | |||
| N-formylpeptide receptor - unspecified 2 | |||
| NG2 | |||
| NGF | NGF | ||
| NK1 receptor | NK1; NK-1 receptor; NK-1R; SPR; Tachykinin receptor 1; Substance-P receptor | ||
| NK2 receptor | NK2; NK-2 receptor; NK-2R; Neurokinin A receptor; SKR; Tachykinin receptor 2; Substance-K receptor | ||
| NK3 receptor | NK3 | ||
| NMDA-type glutamate-gated cationic channel | NMDA receptor NMDA NMDAR |
Tetrameric receptor, consisting of two glycine binding NR1 subunits and two glutamate binding NR2 subunits. The glycine-binding NR3 subunits can also assemble with NR2 subunits. NR1 and NR3 subunits assemble only in xenopus oocytes to form a glycine gated receptor.
NMDA receptors bind glutamate, aspartate, NMDA, NMDA receptors' conductance is modified by glycine, Magnesium, Zinc and 2-amino-5-phosphonovalerate (APV) Laube et al., suggest that the recombinant NMDA receptor is a tetramer (PMID: 9526012, also see PMID: 18779583). |
|
| NMDAR2A | GRIN2A N-methyl D-aspartate receptor subtype 2A NMDA receptor subunit epsilon-1 |
2A subunit of NMDA receptor | |
| NMDAR2B | GRIN2B N-methyl D-aspartate receptor subtype 2B NMDA receptor subunit epsilon-2 |
2B subunit of NMDA receptor | |
| NMDAR2D | GRIN2D N-methyl D-aspartate receptor subtype 2D NR2D NMDA receptor subunit epsilon-4 |
||
| NMU1 receptor | NMU1 | ||
| NMU2 receptor | NMU2 | ||
| NNT-1 | CLCF-1 cardiotrophin-like cytokine factor-1 B cell-stimulating factor-3 Novel Neurotrophin-1 BSF-3 |
||
| NOP receptor | NOP | ||
| NPBW1 receptor | NPBW1 | ||
| NPBW2 receptor | NPBW2 | ||
| NPFF1 receptor | NPFF1 | ||
| NPFF2 receptor | NPFF2 | ||
| NPS receptor | NPS; G-protein coupled receptor 154; G-protein coupled receptor PGR14; G-protein coupled receptor for asthma susceptibility | ||
| NT-3 | Neurotrophin-3 | ||
| NTS1 receptor | NTS1 | ||
| NTS2 receptor | NTS2; Levocabastine-sensitive neurotensin receptor; NT-R-2; NTR2 receptor Neurotensin receptor type 2 | ||
| Nav beta | |||
| Nav beta1 | |||
| Nav beta2 | |||
| Nav beta3 | |||
| Nav beta4 | |||
| Nav1.1 | brain type I; rat I; R-I; Sodium channel protein type I subunit alpha; Sodium channel protein brain I subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.1; Sodium channel protein type subunit alpha |
||
| Nav1.2 | R-II; brain type II; rat II; HBSC II; Sodium channel protein type II subunit alpha; Sodium channel protein brain II subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.2; Sodium channel protein type 2 subunit alpha |
||
| Nav1.3 | rat 3; brain type 3; R-III; Sodium channel protein type III subunit alpha; Sodium channel protein brain III subunit alpha; Voltage- gated sodium channel subtype III; Voltage-gated sodium channel subunit alpha Nav1.3; Sodium channel protein type 3 subunit alpha |
||
| Nav1.4 | SkM1; m1; SkM1; Sodium channel protein type IV subunit alpha; Sodium channel protein skeletal muscle subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4; Sodium channel protein type 4 subunit alpha |
||
| Nav1.5 | skm II; hI; cardiac sodium channel; HH1; Sodium channel protein type V subunit alpha; Sodium channel protein cardiac muscle alpha-subunit; Voltage-gated sodium channel subunit alpha Nav1.5; Sodium channel protein type 5 subunit alpha |
||
| Nav1.6 | NaCh6; PN4; CerIII; Sodium channel protein type VIII subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.6; Sodium channel protein type 8 subunit alpha | ||
| Nav1.7 | Nas; hNE-Na; PN1; Neuroendocrine sodium channel; Peripheral sodium channel 1; Sodium channel protein type IX subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.7; hNE-Na Sodium channel protein type 9 subunit alpha | ||
| Nav1.8 | SNS; PN3; Peripheral nerve sodium channel 3; Sodium channel protein type X subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.8; hPN3; Sodium channel protein type 10 subunit alpha | ||
| Nav1.9 | NaN; SNS-2; Peripheral nerve sodium channel 5; Sensory neuron sodium channel 2; Sodium channel protein type XI subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.9; hNaN; Sodium channel protein type 1subunit alpha | ||
| Nax | NaG Atypical sodium channel |
||
| Nestin | A large intermediate filament protein (class Type VI) expressed during development | ||
| Netrin | Laminin-related secreted protein family involved in axonal guidance | ||
| NeurabinI | PDZ containing proteins with F-actin binding protein activity. | ||
| Neurexin | |||
| Neurofascin | |||
| Neurofilament 150kD mRNA | Neurofilament Medium mRNA NF-M mRNA |
||
| Neurofilament 150kd | Neurofilament Medium NF-M |
Neurofilmanet protein with molecular weight 150 kd. | |
| Neurofilament 200kD mRNA | Neurofilament Heavy mRNA NF-H mRNA |
||
| Neurofilament 200kd | Neurofilament Heavy NF-H |
Neurofilament protein with molecular weight 200 kd. | |
| Neurofilament 68kD mRNA | Neurofilament Light mRNA NF-L mRNA |
||
| Neurofilament 68kd | Neurofilament Light NF-L Neurofilament light polypeptide |
Neurofilament protein with molecular weight approximately 68 kd. | |
| Neurofilament Protein | |||
| Neurokinin | |||
| Neurokinin A | |||
| Neurokinin B | |||
| Neuromedin B | |||
| Neuromedin U | |||
| Neuromedin U receptor | |||
| Neuronal acetylcholine receptor subunit alpha-10 | cholinergic receptor nicotinic alpha 10 Cholinergic receptor nicotinic alpha 10 CHRNA10 NACHR alpha 10 |
A protein that is a translation product of the CHRNA10 gene or a 1:1 ortholog thereof. This nAchR subunit is required for the normal function of the olivocochlear system which is part of the auditory system. Furthermore selective block of α9α10 nicotinic acetylcholine receptors by the conotoxin RgIA has been shown to be analgesic in an animal model of nerve injury pain. (Adapted from PRotein Ontology and Wikipedia). | |
| Neuronal acetylcholine receptor subunit alpha-2 | Nicotinic α2 receptor CHOLINERGIC RECEPTOR NEURONAL NICOTINIC ALPHA POLYPEPTIDE 2 CHRNA2 Nicotinic alpha 2 receptor Alpha 2 Acetylcholine receptor |
A protein that is a translation product of the CHRNA2 gene or a 1:1 ortholog thereof. Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission.(Provided by RefSeq and PRotein Ontology). | |
| Neuronal acetylcholine receptor subunit alpha-4 | CHRNA4 EBN BFNC EBN1 NACHR NACRA4 NACHRA FLJ95812 cholinergic receptor nicotinic alpha 4 Nicotinic alpha 4 receptor Nicotinic α4 receptor |
A protein that is a translation product of the CHRNA4 gene or a 1:1 ortholog thereof. | |
| Neuronal acetylcholine receptor subunit alpha-6 | Cholinergic receptor nicotinic alpha 6 Nica6 CHRNA6 NACHR alpha 6 |
A protein that is a translation product of the CHRNA6 gene or a 1:1 ortholog thereof. The α6 subunit found in certain types of nicotinic acetylcholine receptors found primarily in the brain. Neural nicotinic acetylcholine receptors containing α6 subunits are expressed on dopamine-releasing neurons in the midbrain, and dopamine release following activation of these neurons is thought to be involved in the addictive properties of nicotine. Due to their selective localisation on dopaminergic neurons, α6-containing nACh receptors have also been suggested as a possible therapeutic target for the treatment of Parkinson's disease.(Adapted from PRotein Ontology and Wikipedia). | |
| Neuronal acetylcholine receptor subunit alpha-9 | nicotinic acetylcholine receptor subunit alpha 9 NACHR alpha 9 CHRNA9 Cholinergic receptor nicotinic alpha 9 HSA243342 MGC142109 MGC142135 |
A protein that is a translation product of the CHRNA9 gene or a 1:1 ortholog thereof. This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells. (Adapted from PRotein Ontology and Entrez Gene). | |
| Neuronal acetylcholine receptor subunit beta-2 | CHRNB2 EFNL3 nAChRB2 Cholinergic receptor nicotinic beta 2 |
A protein that is a translation product of the CHRNB2 gene or a 1:1 ortholog thereof. Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. (Adapted from PRotein Ontoloty and Entrez Gene). | |
| Neuronal acetylcholine receptor subunit beta-3 | Cholinergic receptor nicotinic beta 3 CHRNB3 NACRB3 |
A protein that is a translation product of the CHRNB3 gene or a 1:1 ortholog thereof. (Adapted from PRotein Ontology). | |
| Neuronal acetylcholine receptor subunit beta-4 | Acrb4 Neuronal Acetylcholine Receptor Subunit Beta-4 CHRNB4 Cholinergic receptor nicotinic beta 4 |
A protein that is a translation product of the CHRNB4 gene or a 1:1 ortholog thereof. The neuronal acetylcholine receptor is composed of an alpha and a beta subunit. Neuronal acetylcholine receptor beta-4 subunit can be combined with alpha- 2, alpha-3 or alpha-4 to give rise to functional receptor complexes. (Adapted from UniProtKB/Swiss-Prot) | |
| Neuronal nuclear antigen | A 46/48KD DNA-binding, neuron-specific protein found in nuclei which is present in most vertebrate CNS and PNS neuronal cell types | ||
| Neuropeptide AF receptor | |||
| Neuropeptide B | |||
| Neuropeptide B receptor | |||
| Neuropeptide FF | |||
| Neuropeptide FF/neuropeptide AF receptor | |||
| Neuropeptide S | |||
| Neuropeptide S receptor | |||
| Neuropeptide W | |||
| Neuropeptide W/neuropeptide B receptor | |||
| Neuropeptide Y | |||
| Neuropeptide Y receptor | |||
| Neuropeptide head activator | |||
| Neurotensin | |||
| Neurotensin receptor | |||
| Neurotrophin | Family of polypeptide growth factors produced by peripheral target tissues as well as the nervous system, which are critical to neuronal growth, regeneration, survival, and differentiation (CSP). | ||
| Neurotrophin-4 | NT-5 NTF4 NT-4/5 NT-4 |
||
| Nicotinic acid | pyridine-3-carboxylic acid | ||
| Nicotinic acid receptor | |||
| Nicotinic acid receptor - unspecified 1 | G-protein coupled receptor 109A; G-protein coupled receptor HM74A; Nicotinic acid receptor 1 | ||
| Nicotinic acid receptor - unspecified 2 | G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; Nicotinic acid receptor 2 | ||
| Nicotinic acid receptor - unspecified 3 | |||
| Nitric oxide | NO | ||
| Nitric oxide synthase | |||
| Nociceptin | orphanin FQ | ||
| Non-ABeta component | An alpha-Synuclein fragment found in amyloid plaques in Alzheimer's disease. | ||
| Nuclear DNA | |||
| Nucleic Acid | High molecular weight polymers containing a mixture of purine and pyrimidine nucleotides chained together by ribose or deoxyribose linkages (MSH). | ||
| Nucleoside | |||
| Nucleotide | |||
| OT receptor | OT; OT-R; Oxytocin receptor | ||
| OX1 receptor | OX1 | ||
| OX2 receptor | OX2 | ||
| OXE receptor | OXE | ||
| Obestatin | |||
| Oleoylethanolamide | |||
| Olig2 | |||
| Opioid peptide | |||
| Opioid receptor | |||
| Opsin-like receptor | |||
| Opsin-like receptor - unspecified 1 | |||
| Orexin | hypocretin | ||
| Orexin (hypocretin) receptor | |||
| Orexin A | hypocretin 1 | ||
| Orexin B | hypocretin 2 | ||
| Orphan (Chemokine receptor-like) | |||
| Orphan (Chemokine receptor-like) - unspecified 1 | |||
| Orphan (Mas-related) receptor | |||
| Orphan (Mas-related) receptor - unspecified 1 | |||
| Orphan (Mas-related) receptor - unspecified 10 | |||
| Orphan (Mas-related) receptor - unspecified 2 | |||
| Orphan (Mas-related) receptor - unspecified 3 | |||
| Orphan (Mas-related) receptor - unspecified 4 | |||
| Orphan (Mas-related) receptor - unspecified 5 | |||
| Orphan (Mas-related) receptor - unspecified 6 | |||
| Orphan (Mas-related) receptor - unspecified 7 | |||
| Orphan (Mas-related) receptor - unspecified 8 | |||
| Orphan (Mas-related) receptor - unspecified 9 | |||
| Orphan (P2Y-like) receptor | |||
| Orphan (P2Y-like) receptor - unspecified 1 | |||
| Orphan (melatonin-like) receptor | |||
| Orphan (melatonin-like) receptor - unspecified 1 | |||
| Orphan (trace amine-like) receptor | |||
| Orphan (trace amine-like) receptor - unspecified 1 | |||
| Orphan (trace amine-like) receptor - unspecified 2 | |||
| Orphan (trace amine-like) receptor - unspecified 3 | |||
| Orphan receptor | |||
| Orphan receptor - unspecified 1 | |||
| Orphan receptor - unspecified 2 | |||
| OrphanA1 receptor | |||
| OrphanA1 receptor - unspecified 1 | |||
| OrphanA1 receptor - unspecified 2 | |||
| OrphanA1 receptor - unspecified 3 | |||
| OrphanA12 receptor | |||
| OrphanA12 receptor - unspecified 1 | |||
| OrphanA12 receptor - unspecified 2 | |||
| OrphanA13 receptor | |||
| OrphanA13 receptor - unspecified 1 | |||
| OrphanA13 receptor - unspecified 2 | |||
| OrphanA14 receptor | |||
| OrphanA14 receptor - unspecified 1 | |||
| OrphanA14 receptor - unspecified 2 | |||
| OrphanA15 receptor | |||
| OrphanA15 receptor - unspecified 1 | |||
| OrphanA15 receptor - unspecified 2 | |||
| OrphanA2 receptor | |||
| OrphanA2 receptor - unspecified 1 | |||
| OrphanA2 receptor - unspecified 2 | |||
| OrphanA3 receptor | |||
| OrphanA3 receptor - unspecified 1 | |||
| OrphanA3 receptor - unspecified 2 | |||
| OrphanA4 receptor | |||
| OrphanA4 receptor - unspecified 1 | |||
| OrphanA4 receptor - unspecified 2 | |||
| OrphanA6 receptor | |||
| OrphanA6 receptor - unspecified 1 | |||
| OrphanA6 receptor - unspecified 2 | |||
| OrphanA7 receptor | |||
| OrphanA7 receptor - unspecified 1 | |||
| OrphanA9 receptor | |||
| OrphanA9 receptor - unspecified 1 | |||
| OrphanA9 receptor - unspecified 2 | |||
| OrphanLGR receptor | |||
| OrphanLGR receptor - unspecified 1 | |||
| OrphanLGR receptor - unspecified 2 | |||
| OrphanLGR receptor - unspecified 3 | |||
| OrphanSREB receptor | |||
| OrphanSREB receptor - unspecified 1 | |||
| OrphanSREB receptor - unspecified 2 | |||
| OrphanSREB receptor - unspecified 3 | |||
| Other Orphan Gene receptor | |||
| Other Orphan Gene receptor - unspecified 1 | |||
| Other Orphan Gene receptor - unspecified 10 | |||
| Other Orphan Gene receptor - unspecified 11 | |||
| Other Orphan Gene receptor - unspecified 12 | |||
| Other Orphan Gene receptor - unspecified 13 | |||
| Other Orphan Gene receptor - unspecified 14 | |||
| Other Orphan Gene receptor - unspecified 15 | |||
| Other Orphan Gene receptor - unspecified 16 | |||
| Other Orphan Gene receptor - unspecified 17 | |||
| Other Orphan Gene receptor - unspecified 18 | |||
| Other Orphan Gene receptor - unspecified 19 | |||
| Other Orphan Gene receptor - unspecified 2 | |||
| Other Orphan Gene receptor - unspecified 20 | |||
| Other Orphan Gene receptor - unspecified 21 | |||
| Other Orphan Gene receptor - unspecified 22 | |||
| Other Orphan Gene receptor - unspecified 23 | |||
| Other Orphan Gene receptor - unspecified 24 | |||
| Other Orphan Gene receptor - unspecified 25 | |||
| Other Orphan Gene receptor - unspecified 26 | |||
| Other Orphan Gene receptor - unspecified 27 | |||
| Other Orphan Gene receptor - unspecified 28 | |||
| Other Orphan Gene receptor - unspecified 29 | |||
| Other Orphan Gene receptor - unspecified 3 | |||
| Other Orphan Gene receptor - unspecified 30 | |||
| Other Orphan Gene receptor - unspecified 30 (nifext 6647) | |||
| Other Orphan Gene receptor - unspecified 31 | |||
| Other Orphan Gene receptor - unspecified 32 | |||
| Other Orphan Gene receptor - unspecified 33 | |||
| Other Orphan Gene receptor - unspecified 34 | |||
| Other Orphan Gene receptor - unspecified 35 | |||
| Other Orphan Gene receptor - unspecified 36 | |||
| Other Orphan Gene receptor - unspecified 37 | |||
| Other Orphan Gene receptor - unspecified 38 | |||
| Other Orphan Gene receptor - unspecified 39 | |||
| Other Orphan Gene receptor - unspecified 4 | |||
| Other Orphan Gene receptor - unspecified 40 | |||
| Other Orphan Gene receptor - unspecified 41 | |||
| Other Orphan Gene receptor - unspecified 42 | |||
| Other Orphan Gene receptor - unspecified 43 | |||
| Other Orphan Gene receptor - unspecified 5 | |||
| Other Orphan Gene receptor - unspecified 6 | |||
| Other Orphan Gene receptor - unspecified 7 | |||
| Other Orphan Gene receptor - unspecified 8 | |||
| Other Orphan Gene receptor - unspecified 9 | |||
| Oxytocin | Pitocin Syntocinon Oxytocin (BAM Biotech) Pitocin (Parke-Davis) Syntocinon (Sandoz) |
Synthetic 9 residue cyclic peptide. The hormone is prepared synthetically to avoid possible contamination with vasopressin (ADH) and other small polypeptides with biologic activity. Pharmacology: Used to induce labor or to enhance uterine contractions during labor. Uterine motility depends on the formation of the contractile protein actomyosin under the influence of the Ca2+-dependent phosphorylating enzyme myosin light-chain kinase. Oxytocin promotes contractions by increasing the intracellular Ca2+, which in turn activates myosins light chain kinase.. Oxytocin has specific receptors in the muscle llining of the uterus and the receptor concentration increases greatly during pregnancy, reaching a maximum in early labor at term. Mechanism of action: Binds the oxytocin receptor which leads to an increase in intracellular calcium levels. Drug type: Approved. Biotech. Drug category: Anti-tocolytic Agents. Labor Induction Agents. Oxytocics | taken from DrugBank |
| Oxytocin receptor | |||
| P25 | p25alpha TPPP Tubulin Polymerization Promoting Protein |
Should be "p25" with a lower case p, not a Capital P. | |
| P2Y receptor | |||
| P2Y receptor - unspecified 1 | |||
| P2Y1 receptor | P2Y1 | ||
| P2Y11 receptor | P2Y11 | ||
| P2Y12 receptor | P2Y12; ADP-glucose receptor; ADPG-R; P2T(AC); P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12 platelet ADP receptor; SP1999; P2Y purinoceptor 12 | ||
| P2Y13 receptor | P2Y13 | ||
| P2Y2 receptor | P2Y2; ATP receptor; P2U purinoceptor 1; P2U1; Purinergic receptor; P2Y purinoceptor 2 | ||
| P2Y4 receptor | P2Y4 | ||
| P2Y6 receptor | P2Y6 | ||
| PAF receptor | PAF | ||
| PAR1 receptor | PAR1 | ||
| PAR2 receptor | PAR2 | ||
| PAR3 receptor | PAR3 | ||
| PAR4 receptor | PAR4 | ||
| PHF-tau | Hyperphosphorylated tau | ||
| PKR1 receptor | PKR1 | ||
| PKR2 receptor | PKR2 | ||
| PRRP receptor | PRRP | ||
| PSD95 | |||
| Pancreatic polypeptide | |||
| Parathyroid hormone | |||
| Parkin | A cytoplasmic neuronal protein containing two ring-finger domains and a ubiquitin-like dmain at its amino terminus. | ||
| Parvalbumin | |||
| Pentameric ion channel | |||
| Peptide | A short polymers of amino acids. Although somewhat arbitrary, peptides are generally less than 50 amino acids in length. | ||
| Peptide P518 receptor | |||
| Phalloidin | Phalloidin is a peptide derived from the Death Cap mushroom that acts as a toxin by binding actin, inhibiting its depolymerization. Phalloidin binds specifically F-actin and is therefore a very convenient tool to investigate the distribution of F-actin since fluorescent analogs can be synthesized that retain actin binding. (Wikipedia) | ||
| Phenylethanolamine N-Methyltransferase | Phenylethanolamine N Methyltransferase Methyltransferase Norepinephrine Norepinephrine N Methyltransferase Phenethanolamine N Methyltransferase Noradrenalin N Methyltransferase Noradrenaline N Methyltransferase Phenethanolamine N-Methyltransferase Norepinephrine Methyltransferase; Norepinephrine N-Methyltransferase Noradrenaline N-Methyltransferase Noradrenalin N-Methyltransferase S-Adenosyl-L-methionine:phenylethanolamine N-methyltransferase PHENYLETHANOLAMINE METHYLTRANSFERASE N PHENETHANOLAMINE METHYLTRANSFERASE N |
A methyltransferase that catalyzes the reaction of S-adenosyl-L-methionine and phenylethanolamine to yield S-adenosyl-L-homocysteine and N-methylphenylethanolamine. It can act on various phenylethanolamines and converts norepinephrine into epinephrine. (From Enzyme Nomenclature, 1992) EC 2.1.1.28. (adapted from MSH) | |
| Phospholipid | |||
| Pituitary Adenylate Cyclase activating polypeptide | |||
| Platelet Derived Growth Factor | Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication (MSH). | ||
| Platelet-activating factor | |||
| Platelet-activating factor receptor | |||
| Polyclonal antibody | Polyclonal Polyclonal antibodies |
||
| Prion Protein | |||
| Prokineticin | |||
| Prokineticin 1 | |||
| Prokineticin 2 | |||
| Prokineticin receptor | |||
| Prolactin releasing peptide receptor | |||
| Prolactin-releasing peptide | |||
| Prostacyclin | |||
| Prostaglandin D2 | |||
| Prostaglandin E2 | |||
| Prostaglandin F2a | |||
| Prostaglandin lipid | |||
| Prostanoid lipid | |||
| Prostanoid receptor | |||
| Prostanoid receptor - unspecified 1 | |||
| Protease-activated receptor | |||
| Proteasome | A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. | ||
| Protein | |||
| Proteoglycan | |||
| Protocadherin | |||
| Purine Nucleoside | |||
| Purine Nucleotide | |||
| Pyrimidine Nucleoside | |||
| Pyrimidine Nucleotide | |||
| QRFP receptor | QRFP | ||
| RF-amide P518 gene product | |||
| RIM1 | |||
| RNA | A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed) (MSH) | ||
| RXFP1 receptor | RXFP1 | ||
| RXFP2 receptor | RXFP2 | ||
| RXFP3 receptor | RXFP3 | ||
| RXFP4 receptor | RXFP4 | ||
| Red fluorescent protein | |||
| Relaxin | |||
| Relaxin 3 | Relaxin-3 | ||
| Relaxin peptide receptor | |||
| Resolvin E1 | |||
| Retinoic acid receptor responder | |||
| Retinoic acid receptor responder (tazarotene induced) 2 | |||
| Rho GTPase | A large family of monomeric GTP-binding proteins that are involved in regulation of actin organization, gene expression and cell cycle progression. EC 3.6.1.- (MSH). | ||
| Ribosomal RNA | The most abundant form of RNA. Together with proteins, it forms the ribosomes, playing a structural role and also a role in ribosomal binding of mRNA and tRNAs. Individual chains are conventionally designated by their sedimentation coefficients. In eukaryotes, four large chains exist, synthesized in the nucleolus and constituting about 50% of the ribosome. (Dorland, 28th ed) (MSH) | ||
| S100 beta | |||
| S1P1 receptor | S1P1 | ||
| S1P2 receptor | S1P2 | ||
| S1P3 receptor | S1P3 | ||
| S1P4 receptor | S1P4 | ||
| S1P5 receptor | S1P5 | ||
| SAP90 | |||
| SAP97 | |||
| SERCA | Calcium pump found in the membrane of the smooth endoplasmic reticulum. | ||
| SERCA1 | |||
| SERCA2 | |||
| SERCA2a | |||
| SERCA2b | |||
| SERCA3 | |||
| SPC/LPC receptor | |||
| SPC/LPC receptor - unspecified 1 | |||
| SPC/LPC receptor - unspecified 2 | |||
| SPC/LPC receptor - unspecified 3 | |||
| SPC/LPC receptor - unspecified 4 | |||
| SUR1 | |||
| SUR2 | |||
| SUR3 | |||
| Serine protease | |||
| Serotonin | 5-hydroxytryptamine 5-HT; 5HT transporter; 5HTT; Sodium-dependent serotonin transporter |
A biochemical messenger and regulator, synthesized from the essential amino acid L-tryptophan. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (receptors, serotonin) explain the broad physiological actions and distribution of this biochemical mediator (MSH). | |
| Serotonin G-protein coupled receptor | 5-hydroxytryptamine receptor | ||
| Serotonin-gated anionic channel | 5-HT mod-1 receptor Serotonin receptor mod-1 |
||
| Serotonin-gated channel (5-HT3) | Serotonin 5-HT3 receptor; 5-HT-3; 5-HT3R; 5-hydroxytryptamine 3 receptor precursor; Serotonin-gated ion channel receptor 5-hydroxytryptamine 3 receptor |
||
| Sidekick | |||
| Sodium channel - type 1 | |||
| Somatostatin | |||
| Somatostatin receptor | |||
| Spectrin | Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins (Gene Ontology). | ||
| Sphingolipid | |||
| Sphingosine | |||
| Sphingosine 1-phosphate | |||
| Spinophilin | neurabinII | ||
| Sst1 receptor | sst1; SRIF-2; SS1R; Somatostatin receptor type 1 | ||
| Sst2 receptor | sst2 | ||
| Sst3 receptor | sst3 | ||
| Sst4 receptor | sst4 | ||
| Sst5 receptor | sst5; SS5R; Somatostatin receptor type 5 | ||
| Stathmin | |||
| Steroid | |||
| Substance P | |||
| Succinate | |||
| Sulfonylurea receptor | SUR | ||
| Synapse associated protein 102 | Disks large homolog 3 | ||
| Synapsin | A family of synaptic vesicle-associated proteins involved in the short-term regulation of neurotransmitter release. Synapsin I (Protein I), the predominant member of this family, links synaptic vesicles to actin filaments in the presynaptic nerve terminal. These interactions are modulated by the reversible phosphorylation of synapsin I through various signal transduction pathways. The protein is also a substrate for cAMP- and calcium-calmodulin-dependent protein kinases. It is believed that these functional properties are also shared by synapsin II (Protein III) (MSH). | ||
| Synaptobrevin I | VAMP-1 Vesicle-associated membrane protein 1 |
A protein that is a translation product of the VAMP1 gene or a 1:1 ortholog thereof (PRotein Ontology). | |
| Synaptophysin | Synaptophysin is a synaptic vesicle membrane protein | ||
| Synaptotagmin 1 | |||
| Syndecan | Family of transmembrane heparan sulfate proteoglycans (CSP - Bonfire). | ||
| Syndecan-2 | fibroglycan | ||
| Synoretin | A synaptic protein expressed predominantly in the outer nuclear retinal layer. It is expressed, at a lower level, in the brain. | ||
| Synphilin-1 | A 919-amino-acid protein that interacts with alpha-synuclein. | ||
| Synuclein Protein | Synuclein is a small, soluble protein primarily expressed in neural tissue and in certain tumors. The synuclein family includes three known proteins: alpha-Synuclein, beta-Synuclein and gamma-Synuclein. | ||
| TA1 receptor | TA1; TaR-1; Trace amine receptor 1; Trace amine-associated receptor 1 | ||
| TA3 receptor | TA3 | ||
| TA4 receptor | TA4 | ||
| TA5 receptor | TA5 | ||
| TP receptor | TP | ||
| TPC1 | two-pore channel-1 | ||
| TPC2 | two-pore channel-2 | ||
| TRH receptor | TRH | ||
| … further results | |||
