arrow

From NeuroLex

(Redirected from Nif-0000-00192)
Jump to: navigation, search



Resource:Harvard Brain Tissue Resource Center

Name: Resource:Harvard Brain Tissue Resource Center
Description: Established at McLean Hospital as a centralized resource for the collection and distribution of human brain specimens for brain research. This is a national resource for the acquisition, processing, storage, distribution of high quality postmortem brain specimens for brain research. Specimens are obtained at no charge via a request form downloaded at website.

Research over the past decade has shown that the study of human brain tissue is essential to increasing our understanding of how the nervous system functions. Most recently, postmortem human brain research has played a significant role in the development of a genetic test for Huntington's disease as well as a treatment for Parkinson's disease. Similarly, neurochemical and anatomical studies focusing on the biological nature of the severe mental illnesses are now emerging and bringing forth new hope for understanding the underlying brain mechanisms responsible for psychosis and other symptoms associated with these debilitating brain disorders. In order to perform research into the neurological or psychiatric disorders, it is vital to collect normal control tissue as well.

Scientists from the nation's top research and medical centers request tissue from The Brain Bank for their investigations. Since the majority of these studies can be carried out on a very small amount of tissue, each donated brain provides a large number of samples for many researchers. However, in order to conduct valid experiments, it is necessary to supply researchers with a variety of brain specimens.

Various types of brain tissue are collected including those with neurological and psychiatric disorders, and their parents, siblings and offspring. The HBTRC maintains the most extensive collection of postmortem human brains from individuals with Huntington’s chorea, Alzheimer’s disease, Parkinson’s disease, and a growing number of other neurological disorders. In addition, the HBTRC also has a significant collection of brains from individuals diagnosed with schizophrenia and manic depressive illness, as well as "normal-control" specimens that are essential as a comparison group for all of these brain disorders. The Brain Tissue Resource Center is interested in collecting tissue from individuals diagnosed with various other disorders not mentioned.

With the NIH funding that supports the HBTRC, all disbursements are made at no cost to the recipient laboratory.

See the National Brain Databank for gene expression data related to samples.
Other Name(s): Harvard Brain Bank, The Brain Bank
Abbreviation: HBTRC
Parent Organization: Harvard Medical School; Massachusetts; USA, McLean Hospital; Massachusetts; USA
Supporting Agency: National Institutes of Health, Private organizations, NIH Blueprint for Neuroscience Research
Resource Type(s): Brain bank, Tissue bank, Biospecimen repository
Resource: Resource
URL: http://www.brainbank.mclean.org/
*Id: nif-0000-00192
Related condition/disease: Huntington's disease, Parkinson's disease, Healthy, Mental disease, Neurological disorder, Normal control, Alzheimer's disease, Schizophrenia, Bipolar Disorder, Relative, Parent, Sibling, Child, Lewy Body Variant Alzheimer's disease, Amyotrophic Lateral Sclerosis, Dementia, Unipolar Depressive Dissorder, Diffuse Lewy Body Disease, DYT-1 Dystonia, Progressive Supranuclear Palsy, Rett Syndrome, Tourette's Syndrome
Related application: Research
Processing: Fresh quick-frozen, Block, Coronal section, Nitrogen vapor frozen, Dry ice frozen, Passive frozen, Formalin-fixed, Frozen
Related to: Resource:One Mind Biospecimen Bank Listing, US Biobank
Availability: Public
Address: Harvard Brain Tissue Resource Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478 Telephone:1-800-BRAIN-BANK (1-800-272-4622) Fax: (617) 855-3199
Keywords: Brain tissue, Brain, Tissue, Cerebral Spinal Fluid, Fresh quick-frozen, Block, Coronal section, Nitrogen vapor frozen, Dry ice frozen, Passive frozen, Formalin-fixed, Frozen, Huntington's disease, Parkinson's disease, Healthy, Mental disease, Neurological disorder, Normal control, Alzheimer's disease, Schizophrenia, Bipolar Disorder, Relative, Parent, Sibling, Child, Lewy Body Variant Alzheimer's disease, Amyotrophic Lateral Sclerosis, Dementia, Unipolar Depressive Disorder, Diffuse Lewy Body Disease, DYT-1 Dystonia, Progressive Supranuclear Palsy, Rett Syndrome, Tourette's Syndrome, Restless Legs Syndrome, Autism, Post-mortem, Late adult human, Data set, Gene expression
Organism: Human
Link to OWL / RDF: Download this content as OWL/RDF

Categories related to Resource:Harvard Brain Tissue Resource Center

Resource:Autism Tissue Program

Parts of Resource:Harvard Brain Tissue Resource Center

Curation status: Uncurated

This resource will be curated within 7 days.

For Resource Owners:
After the resource is curated, you may create a sitemap, which will help keep your registry description up-to-date and inform search engines about your resource.

Note: For a new resource, the website's URL must first be verified by a NIF curator before you may proceed.

Learn more about what NIF can do for your resource.
Proudly proclaim your inclusion in NIF by displaying the "Registered with NIF" button on your site. Please login to create the sitemap. (top right)

Notes

This page uses this default form:Resource

Contributors

Aarnaud, Bandrow, Ccdbuser, Nifbot2



bookmark

*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.

Facts about Resource:Harvard Brain Tissue Resource CenterRDF feed
AbbrevHBTRC  +
AddressHarvard Brain Tissue Resource Center  +, McLean Hospital  +, 115 Mill Street  +, Belmont  +, and MA 02478 Telephone:1-800-BRAIN-BANK (1-800-272-4622) Fax: (617) 855-3199  +
AvailabilityPublic  +
CommentSample type: Brain tissue, Brain, Tissue, Cerebral Spinal Fluid
CurationStatuscurated  +
DefiningCitationhttp://www.brainbank.mclean.org/  +
DefinitionEstablished at McLean Hospital as a centra Established at McLean Hospital as a centralized resource for the collection and distribution of human brain specimens for brain research. This is a national resource for the acquisition, processing, storage, distribution of high quality postmortem brain specimens for brain research. Specimens are obtained at no charge via a request form downloaded at website.

Research over the past decade has shown that the study of human brain tissue is essential to increasing our understanding of how the nervous system functions. Most recently, postmortem human brain research has played a significant role in the development of a genetic test for Huntington's disease as well as a treatment for Parkinson's disease. Similarly, neurochemical and anatomical studies focusing on the biological nature of the severe mental illnesses are now emerging and bringing forth new hope for understanding the underlying brain mechanisms responsible for psychosis and other symptoms associated with these debilitating brain disorders. In order to perform research into the neurological or psychiatric disorders, it is vital to collect normal control tissue as well. Scientists from the nation's top research and medical centers request tissue from The Brain Bank for their investigations. Since the majority of these studies can be carried out on a very small amount of tissue, each donated brain provides a large number of samples for many researchers. However, in order to conduct valid experiments, it is necessary to supply researchers with a variety of brain specimens. Various types of brain tissue are collected including those with neurological and psychiatric disorders, and their parents, siblings and offspring. The HBTRC maintains the most extensive collection of postmortem human brains from individuals with Huntingtonâ??s chorea, Alzheimerâ??s disease, Parkinsonâ??s disease, and a growing number of other neurological disorders. In addition, the HBTRC also has a significant collection of brains from individuals diagnosed with schizophrenia and manic depressive illness, as well as "normal-control" specimens that are essential as a comparison group for all of these brain disorders. The Brain Tissue Resource Center is interested in collecting tissue from individuals diagnosed with various other disorders not mentioned. With the NIH funding that supports the HBTRC, all disbursements are made at no cost to the recipient laboratory.

See the National Brain Databank for gene expression data related to samples.
r gene expression data related to samples.
ExampleImageHarvard Brain Tissue Resource Center.PNG  +
Has default formThis property is a special property in this wiki.Resource  +
Has roleBrain bank  +, Tissue bank  +, and Biospecimen repository  +
Idnif-0000-00192  +
Is part ofHarvard Medical School; Massachusetts; USA  +, and McLean Hospital; Massachusetts; USA  +
KeywordsBrain tissue  +, Brain  +, Tissue  +, Cerebral Spinal Fluid  +, Fresh quick-frozen  +, Block  +, Coronal section  +, Nitrogen vapor frozen  +, Dry ice frozen  +, Passive frozen  +, Formalin-fixed  +, Frozen  +, Huntingtons disease  +, Parkinsons disease  +, Normal  +, Mental disease  +, Neurological disorder  +, Normal control  +, Alzheimers disease  +, Schizophrenia  +, Bipolar Disorder  +, Relative  +, Parent  +, Sibling  +, Child  +, Lewy Body Variant Alzheimer's disease  +, Amyotrophic Lateral Sclerosis  +, Dementia  +, Unipolar Depressive Disorder  +, Diffuse Lewy Body Disease  +, DYT-1 Dystonia  +, Progressive Supranuclear Palsy  +, Rett Syndrome  +, Tourette's Syndrome  +, Restless Legs Syndrome  +, Autistic Disorder  +, Post-mortem  +, Late adult human  +, Data set  +, and Gene expression  +
LabelResource:Harvard Brain Tissue Resource Center  +
ListedbyResource:One Mind Biospecimen Bank Listing  +, and US Biobank  +
ModifiedDate1 October 2014  +
Page has default formThis property is a special property in this wiki.Resource  +
ProcessingFresh quick-frozen  +, Block  +, Coronal section  +, Nitrogen vapor frozen  +, Dry ice frozen  +, Passive frozen  +, Formalin-fixed  +, and Frozen  +
RelatedToResource:One Mind Biospecimen Bank Listing  +
Related applicationResearch  +
Related diseaseHuntingtons disease  +, Parkinsons disease  +, Normal  +, Mental disease  +, Neurological disorder  +, Normal control  +, Alzheimers disease  +, Schizophrenia  +, Bipolar Disorder  +, Relative  +, Parent  +, Sibling  +, Child  +, Lewy Body Variant Alzheimer's disease  +, Amyotrophic Lateral Sclerosis  +, Dementia  +, Unipolar Depressive Dissorder  +, Diffuse Lewy Body Disease  +, DYT-1 Dystonia  +, Progressive Supranuclear Palsy  +, Rett Syndrome  +, and Tourette's Syndrome  +
SpeciesHuman  +
SuperCategoryResource  +
Supporting AgencyNational Institutes of Health  +, Private organizations  +, and Resource:NIH Blueprint for Neuroscience Research  +
SynonymHarvard Brain Bank  +, and The Brain Bank  +