NACC will provide help to researchers locating specific classes of specimens and direct them to the individual ADCs, where they may request access to stored specimens.

NACC developed and maintains a large relational database of standardized clinical and neuropathological research data collected from each ADC, and this database provides a valuable resource for both exploratory and explanatory Alzheimer's disease research. Data are submitted continuously by the participating ADC but are frozen and certified app

An account is NOT necessary to download UDS data collection forms and documentation or to request data from NACC. Any researcher, whether affiliated with an ADC or not may request a data file for analysis or aggregate data tables. Aggregate data tables requested are produced and returned as soon as the queue allows (usually within 1-3 days depending on the complexity). Data file requests, for the researchers own analysis, require a brief. 1-2 page description of the intended research and usually some initial consultation with a NACC analyst to ensure that the data elements to be included in the file are adequate to address the research question. The data provided are HIPAA de-identified.

The database consists of several datasets, and searches may be done on the entire database or on individual datasets. Access is granted by security level.
The Minimum Data Set (MDS) - Brief, cross-sectional clinical and demographic data abstracted for subjects enrolled in NIA Alzheimer's Disease Centers 1984 - 2005.
The Uniform Data Set (UDS) - Standardized clinical examination, testing, diagnostic evaluation and data collection protocol with annual longitudinal follow-up. Implemented September 2005 and continuing. Approximately 20,000 subjects have been enrolled in the UDS as of July, 2010. *

Neuropathology Data Set (NP) - Neuropathologic features of subjects who had post-mortem neuropathological examination, 1984 - present. These data include those subjects with MDS and/or UDS clinical data.