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Category:Beta2 receptor
Abbrev B2R  +
Created 19 September 2007  +
CurationStatus uncurated  +
DefiningCitation Entrez Gene  +
Definition Beta adrenergic receptor with 100-fold gre Beta adrenergic receptor with 100-fold greater affinity for epinephrine than norepinephrine. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor's gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. (adapted from Entrez gene) ype 2 diabetes. (adapted from Entrez gene)
Has role Adrenoceptor receptor +, Neurotransmitter Receptor +, G-protein coupled receptor +
Id nifext_7075  +
Is part of Catecholamine system +, Adrenergic system +, Noradrenergic system +
Label Beta2 receptor  +
Modification dateThis property is a special property in this wiki. 22 May 2010 04:47:24  +
ModifiedDate 22 May 2010  +
PMID 7938162  +
RelatedTo Epinephrine +, Norepinephrine +
SuperCategory Protein  +
Synonym beta2; beta 2; b2; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; Beta-2 adrenergic receptor; β2 adrenoreceptor; ADRB2;  +
Categories Protein, Adrenoceptor receptor
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Alprenolol +, Arformoterol +, Bambuterol +, Bisoprolol +, Bitolterol +, Bretylium +, Carteolol +, Carvedilol +, Clenbuterol +, Desipramine +, Epinephrine +, Fenoterol +, Formoterol +, Isoproterenol +, Labetalol +, Levobunolol +, Metipranolol +, Nadolol +, Norepinephrine +, Orciprenaline +, RelatedTo
Beta2 receptor (nifext 7082) + SameAs


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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.