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From NeuroLex
| Abbrev
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B2R +
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| Created
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19 September 2007 +
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| CurationStatus
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uncurated +
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| DefiningCitation
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Entrez Gene +
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| Definition
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Beta adrenergic receptor with 100-fold gre … Beta adrenergic receptor with 100-fold greater affinity for epinephrine than norepinephrine. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor's gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. (adapted from Entrez gene) ype 2 diabetes. (adapted from Entrez gene)
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| Has role
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Adrenoceptor receptor +,
Neurotransmitter Receptor +,
G-protein coupled receptor +
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| Id
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nifext_7075 +
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| Is part of
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Catecholamine system +,
Adrenergic system +,
Noradrenergic system +
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| Label
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Beta2 receptor +
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| Modification dateThis property is a special property in this wiki.
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22 May 2010 04:47:24 +
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| ModifiedDate
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22 May 2010 +
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| PMID
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7938162 +
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| RelatedTo
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Epinephrine +,
Norepinephrine +
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| SuperCategory
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Protein +
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| Synonym
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beta2; beta 2; b2; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; Beta-2 adrenergic receptor; β2 adrenoreceptor; ADRB2; +
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| Categories |
Protein,
Adrenoceptor receptor
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Alprenolol +,
Arformoterol +,
Bambuterol +,
Bisoprolol +,
Bitolterol +,
Bretylium +,
Carteolol +,
Carvedilol +,
Clenbuterol +,
Desipramine +,
Epinephrine +,
Fenoterol +,
Formoterol +,
Isoproterenol +,
Labetalol +,
Levobunolol +,
Metipranolol +,
Nadolol +,
Norepinephrine +,
Orciprenaline +,
…
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RelatedTo
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Beta2 receptor (nifext 7076) +,
Beta2 receptor (nifext 7079) +,
Beta2 receptor (nifext 7082) +
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SameAs
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