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Comment taken from DrugBank
CurationStatus uncurated  +
Curator Ab +
DefiningCitation  +
Definition A strong organic base existing primarily a A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC. (PubChem) Pharmacology: Guanidine apparently acts by enhancing the release of acetylcholine following a nerve impulse. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes. Mechanism of action: Not Available Drug type: Approved. Small Molecule. Drug category: Parasympathomimetics ecule. Drug category: Parasympathomimetics
Has role Drug +
Id CHEBI:42820  +
Label Guanidine  +
Modification dateThis property is a special property in this wiki. 12 August 2014 00:19:49  +
ModifiedDate 12 August 2014  +
RelatedTo Aldehyde dehydrogenase +, Mitochondrial +, DNA +, Lysozyme +, Ribonuclease pancreatic +, Discs large homolog 4 +, Argininosuccinate synthase +, Guanidinoacetate N-methyltransferase +, Divalent-cation tolerance protein cutA +, Arginase +
SuperCategory Molecular entity  +
Synonym Aminomethanamidine  +, Carbamamidine  +, Carbamidine  +, Guanidin  +, Guanidine Hydrochloride  +, Guanidinium Chloride  +, Guanidinium Sulfate  +, Imidourea  +, Iminourea  +, Guanidine hydrochloride  +
Categories Molecular entity
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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.