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Category:Neuronal nuclear antigen
Abbrev NeuN, Neuna60  +
CurationStatus uncurated  +
Definition A 46/48KD DNA-binding, neuron-specific pro A 46/48KD DNA-binding, neuron-specific protein found in nuclei which is present in most vertebrate CNS and PNS neuronal cell types. NeuN is widely used to label neurons, despite some shortcomings. A few neuronal cell types are not recognized by the NeuN antibody, such as cerebellar Purkinje cells and Golgi cells, olfactory Mitral cells and retinal photoreceptors. However the vast majority of neurons are strongly NeuN positive. NeuN immunoreactivity becomes obvious as neurons mature, typically after they have downregulated expression of Doublecortin, a marker seen in the earliest stages of neuronal development. (Adapted from Wikipedia: pedia:
Has role Neuron specific marker +
Id nlx_152221  +
Label Neuronal nuclear antigen  +
Modification dateThis property is a special property in this wiki. 15 April 2013 00:32:19  +
ModifiedDate 15 April 2013  +
SuperCategory Protein  +
Synonym Feminizing Locus on X-3  +, Fox-3  +, or Hexaribonucleotide Binding Protein-3  +
Categories Protein
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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.