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Category:Resource:NIH Clinical Collection
Abbrev NCC  +
CurationStatus uncurated  +
DefiningCitation http://www.nihclinicalcollection.com  +
Definition A plated array of approximately 450 small A plated array of approximately 450 small molecules that have a history of use in human clinical trials. The collection was assembled by the National Institutes of Health (NIH) through the Molecular Libraries Roadmap Initiative as part of its mission to enable the use of compound screens in biomedical research. Similar collections of FDA approved drugs have proven to be rich sources of undiscovered bioactivity and therapeutic potential. The clinically tested compounds in the NCC are highly drug-like with known safety profiles. These compounds can provide excellent starting points for medicinal chemistry optimization and, for high-affinity targets, may even be appropriate for direct human use in new disease areas. for direct human use in new disease areas.
Has default formThis property is a special property in this wiki. Resource  +
Has role Reagent supplier +, Material resource +
Id nif-0000-00254  +
Is part of BioFocus +
Keywords Clinical +, Collection +, Drug +, Compound +, Chemistry +, Medicinal chemistry +, Target +, Affinity +, Human +, Disease +, Disorder +, Small molecule +
Label Resource:NIH Clinical Collection  +
Modification dateThis property is a special property in this wiki. 26 June 2013 19:21:30  +
ModifiedDate 26 June 2013  +
Page has default formThis property is a special property in this wiki. Resource  +
RelatedTo Molecular Libraries Roadmap Initiative +
SuperCategory Resource  +
Supporting Agency National Institutes of Health +
Categories Resource
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