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Category:1-120 Truncated Alpha-Synuclein Drosophila
Authors Magali Periquet  +, Tudor Fulga  +, Liisa Myllykangas  +, Michael G. Schlossmacher  +, and Mel B. Feany  +
CurationStatus uncurated  +
Definition This transgenic drosophila expresses a for This transgenic drosophila expresses a form of alpha-synuclein that is a C-terminally truncated fragment comprising amino acids 1-120. This form of alpha-synuclein has an enhanced ability to aggregate and thus enhanced neurotoxicity. This mutant is used in research to determine the role of alpha-synuclein aggregation in neurodegenerative diseases, such as Parkinsons. degenerative diseases, such as Parkinsons.
Figure 1-3 +
Id nlx_organ_090801  +
JournalNumber 12 +
JournalVolume 27 +
Label 1-120 Truncated Alpha-Synuclein Drosophila  +
Modification dateThis property is a special property in this wiki. 28 October 2009 01:05:57  +
ModifiedDate 28 October 2009  +
PMID 17376994  +
Pages 3338-3346
PublicationDate March 21 +, 2007 +
PublicationName The Journal of Neuroscience +
Title Aggregated Alpha-Synuclein Mediates Dopaminergic Neurotoxicity In Vivo  +
Categories Mutant Drosophila
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