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Category:Alpha2C receptor
Abbrev A2CR  +
Created 19 September 2007  +
CurationStatus uncurated  +
DefiningCitation Entrez Gene  +
Definition The alpha-2C adrenergic receptor (α2C adre The alpha-2C adrenergic receptor (α2C adrenoreceptor), also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding it. Alpha-2-adrenergic receptors include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. (Adapted from Entrez Gene). erve activity. (Adapted from Entrez Gene).
Has role Adrenoceptor receptor +, Neurotransmitter Receptor +, G-protein coupled recpetor +
Id nifext_7113  +
Is part of Catecholamine system +, Adrenergic system +, Noradrenergic system +
Label Alpha2C receptor  +
Modification dateThis property is a special property in this wiki. 22 May 2010 02:09:20  +
ModifiedDate 22 May 2010  +
PMID 7938162  +
RelatedTo Epinephrine +, Norepinephrine +
SuperCategory Protein  +
Synonym alpha2C; alpha 2C; A2C; Alpha-2 adrenergic receptor subtype C4; Alpha-2C adrenoceptor; Alpha-2C adrenoreceptor; Alpha-2C adrenergic receptor  +, α2C adrenoreceptor  +, ADRA2C;  +
Categories Protein, Adrenoceptor receptor
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Bethanidine +, Brimonidine +, Fenoldopam +, Guanadrel Sulfate +, Guanethidine +, Norepinephrine +, Yohimbine + RelatedTo


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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.