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Category:Beta3 receptor
Abbrev B3R  +
Created 19 September 2007  +
CurationStatus uncurated  +
DefiningCitation PMID: 16457637  +
Definition Beta adrenergic receptor found in brown ad Beta adrenergic receptor found in brown adipose tissue, which stimulates lipolysis and thermogenesis. This receptor class has a low affinity for beta1 and beta2 receptors, but a high affinity for BRL 37344 and its derivatives. It is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Some β3 agonists have demonstrated antistress effects in animal studies, suggesting it also has a role in the CNS. Beta3-Receptors are found in the gallbladder, urinary bladder, and in brain adipose tissue. Their role in gallbladder physiology is unknown, but they are thought to play a role in lipolysis and thermogenesis in brown fat. In the urinary bladder it is thought to cause relaxation of the bladder and prevention of urination. f the bladder and prevention of urination.
Has role Adrenoceptor receptor +
Id nifext_6793  +
Is part of Catecholamine system +, Adrenergic system +, Noradrenergic system +
Label Beta3 receptor  +
Modification dateThis property is a special property in this wiki. 22 May 2010 04:53:46  +
ModifiedDate 22 May 2010  +
PMID 6325935,  +
RelatedTo Epinephrine +, Norepinephrine +
SuperCategory Protein  +
Synonym beta3; beta 3; b;3Beta-3 adrenoceptor; Beta-3 adrenoreceptor; Beta-3 adrenergic receptor; β3 adrenoreceptor; ADRB3;  +
Categories Protein, Adrenoceptor receptor
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Norepinephrine +, Pindolol +, Propranolol + RelatedTo


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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.