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Created 15 August 2007  +
CurationStatus pending_final_vetting  +
DefiningCitation Beck, J.A., et al., Genealogies of mouse inbred strains (2000), Nature, Jan2000, v24, p23  +
ExternallySourcedDefinition Origin: Little 1909 from stock segregating Origin: Little 1909 from stock segregating for coat colour. Oldest of all inbred strains of mice. In 1929-30 crosses were made between substrains, and several new substrains established, including the widely used substrains /1 and /2. Differences between the substrains are probably too large to be accounted for by mutation, and are probably due to substantial residual heterozygosity following the crosses between substrains. Thus DBA/1 and DBA/2 differ at least at the following loci: Car2, Ce2, Hc, H2, If1, Lsh, Tla, and Qa3. With such large differences, they should probably be regarded as different strains rather than substrains of the same strain. In this listing the two are listed separately. DBA/LiA differs from /1 and /2 at the Gpd1 locus, and is similar to DBA/2 at the Tla locus. Note that unfostered substrains carry the mammary tumour virus and have a high indicence of mammary tumours. have a high indicence of mammary tumours.
Id birnlex_380  +
Label DBA  +
Modification dateThis property is a special property in this wiki. 30 May 2009 01:42:09  +
ModifiedDate 30 May 2009  +
SuperCategory Inbred mouse strain  +
Categories Inbred mouse strain
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