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Category:DJ-1 Mutant Drosophila
Authors Marc Meulener  +, Alexander Whitworth  +, Cecilia Armstrong-Gold  +, Patrizia Rizzu  +, Peter Heutink  +, Paul Wes  +, Leo Pallanck  +, Nancy Bonini  +
CurationStatus uncurated  +
Definition This drosophila has had its the DJ-1 gene This drosophila has had its the DJ-1 gene deleted. The DJ-1 mutant helps to protect the organism from oxidative stress. This fly model is viable, fertile, and has a normal number of dopaminergic neurons. However, it has increased sensitivity to oxidative stress and chemical agents. This mutant drosophila is being used in the laboratory to uncover the role of enviornmental toxins acting through oxdative stress on Parkinson's disease. gh oxdative stress on Parkinson's disease.
Id nlx_organ_090805  +
JournalVolume Resource:newResourcetest +
Label DJ-1 Mutant Drosophila  +
Modification dateThis property is a special property in this wiki. 28 October 2009 01:18:37  +
ModifiedDate 28 October 2009  +
PMID 16139213  +
Pages 1572-1577
PublicationDate September 6 +, 2005 +
PublicationName Current Biology +
Title Drosophila DJ-1 Mutants Are Selectively Sensitive to Environmental Toxins Associated with Parkinson's Disease  +
Categories Mutant Drosophila
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