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Category:Neocortex Cajal-Retzius cell
Created 20 October 2008  +
CurationStatus uncurated  +
Curator Maryann Martone +
Definition Neurons of the human embryonic marginal zo Neurons of the human embryonic marginal zone which display, as a salient feature, radial ascending processes that contact the pial surface, and a horizontal axon plexus located in the deep marginal zone. These cells were first described by Retzius (Retzius, 1893, 1894) (see the cell labelled 'Retzius, 1893' in Fig. 1). There is consensus that homologous elements are present in the non-primate neocortex, where their morphology is much simpler, as initially described in 1891 by Cajal (Fig. 2) (Cajal, 1891). \\nThe definition of these cells has remained somewhat confusing, in part because Cajal and Retzius studied different species and different developmental stages, and also because their original publications have not been generally available. Meyer et al (1999)prefer to define 'Cajal\\u2013Retzius cells' loosely, as the family of Reln-immunoreactive (ir) neurons in the marginal zone, and reserve the term of pioneer neurons for the early, Reln-negative preplate derivatives that settle in the MZ and project to sub-cortical levels. Adapted from Meyer et al. (1999) l levels. Adapted from Meyer et al. (1999)
DefinitionSource Meyer, G. et al. (1999) What is a Cajal-Retzius cell? A reassessment of a classical cell type based on recent observations in the developing neocortex. Cerebral Cortex 9 (8), pp 765-775. +
Has default formThis property is a special property in this wiki. Petilla neuron  +
Id nlx_cell_20081206  +
Label Neocortex Cajal-Retzius cell  +
Located in Brain marginal zone +
Modification dateThis property is a special property in this wiki. 9 March 2012 01:19:43  +
ModifiedDate 9 March 2012  +
Page has default formThis property is a special property in this wiki. Petilla neuron  +
Species Human +
SuperCategory Neuron  +
Synonym Cajal-Retzius Cell  +
Categories Neuron
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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.