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Category:Olfactory bulb (main) mitral cell
Abbrev MC  +
AxonDiameter Rat: 1 um +
AxonLength several mm  +
AxonMyelination myelinated  +
AxonProjectionLaterality ipsilateral  +
CellSomaShape Category:Mitral   +
CellSomaSize Large soma  +
CellularSynapticTarget Olfactory bulb (main) granule cell +, Intrinsic: granule cells in granule cell layer and external plexiform layer; possibly Blanes cells in granule cell layer; Extrinsic +, Pyramidal cells of olfactory cortex; superficial interneurons of olfactory cortex +
Created 5 September 2007  +
CurationStatus graph position temporary  +
DefiningCitation Shepherd, Chen and Greer (2004). Olfactory bulb. In The Synaptic Organization of the Brain, ed 5. New York: Oxford University Press.  +
DefiningCriteria Morphology; Connectivity; Biochemical  +
Definition Principal neuron located in the olfactory Principal neuron located in the olfactory bulb in the mammalian central nervous system. The cell bodies are arranged in a thin layer between the granule cell layer and the external plexiform layer. Each mitral cell is usually characterized in the mammal by a single primary dendrite that traverses the external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches which receives input from the axons of olfactory receptor neurons. Axons of the mitral cells project to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala. cortex, olfactory tubercle, and amygdala.
DendriteLength Rat: Apical trunk: 400-500 um; apical tuft: 70-150 um; basal: up to 1 mm +
DendriteThickness Rat: Apical trunk: 2-6; apical tuft: 1-2 um at origin; basal: 2-3 um at origin, narrowing through branching to less than 1 um.  +
EditorialNote I changed protocadherin-2 to Protocadherin gamma-C3, as that seems to be the preferred name in NCBI and the Protein Ontology. Changed TBX-21 to T-box protein 21, to distinguish it from the gene. Please let me know if these changes aren't appropriate. know if these changes aren't appropriate.
ExampleImage Olfactory bulb (main) mitral cell.gif +
FiringPatterns Regular firing and bursting  +
Has default formThis property is a special property in this wiki. Petilla neuron  +
Has role Principal neuron role +
Id nifext_120  +
Label Olfactory bulb (main) mitral cell  +
Located in Olfactory bulb main mitral cell body layer +
LocationOfAxonArborization Olfactory cortex +
LocationOfLocalAxonArborization Olfactory bulb main granule cell layer +, Olfactory bulb main external plexiform layer +
Modification dateThis property is a special property in this wiki. 28 August 2014 19:01:52  +
ModifiedDate 28 August 2014  +
MolecularConstituents T-box protein 21 +, Protocadherin gamma-C3 +
Neurotransmitter Glutamate +
NeurotransmitterReceptors GABA receptor +, AMPA-type glutamate-gated cationic channel +, NMDA +, GABA A-gated anionic channel +, GABA-B Receptor +
NumberOfPrimaryDendrites 1 (applies to most mammals)  +
OriginOfAxon soma and sometimes dendrite  +
Page has default formThis property is a special property in this wiki. Petilla neuron  +
PassiveSubthresholdParameters RN, 20=50 megohm  +
Species Mammal +
SpikingFeatures same  +
SpineDensityOnDendrites Smooth +
SpontaneousFiringPatterns Regular firing and bursting  +
SpontaneousFiringRate medium firing  +
SubcellularSynapticTarget Intrinsic: Dendrodendritic synapses on granule cell dendritic spines. Extrinsic: Axon in olfactory cortical areas on apical dendritic spines of pyramidal cells and dendrites of superficial interneurons  +
SuperCategory Neuron  +
SynapticPhysiology Output synapses at both dendrodendritic and axodendritic synapses: GLU NMDA, AMPA; input synapses: GABA from granule cell dendrodendritic synapses  +
Synonym Mitral neuron  +
Categories Neuron
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Olfactory epithelium main sensory cell + CellularSynapticTarget


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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.