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Category:Pedunculopontine tegmental nucleus
Abbrev PPTg, PPT, PPTg, PPN  +
AbbrevSource  +,  +
AfferentProjections Thalamus +, Brainstem +
Comment These cell groups target a region just med These cell groups target a region just medial to the PPT, Shown in most major textbooks, From the internal segment of the globus pallidus and the substantia nigra pars reticulata, Which Rye et al. have called the midbrain extrapyramidal area (MEA). The actual inputs to the PPT neurons are largely unknown., In fact DOES NOT EXIST (!). Instead, The most widely cited afferent input to the PPT ost widely cited afferent input to the PPT
Coordinates Paxinos and Watson 1998 rat: AP -7.8, DV -7.4, RL 1.8  +
Created 15 July 2006  +
CurationStatus uncurated  +
Curator Bill Bug +
DefiningCitation Rye DB, Saper CB, Lee HJ, Wainer BH. Pedunculopontine tegmental nucleus of the rat: cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum. J Comp Neurol 259:483-428, 1987  +
DefiningCriteria cyto-architecture  +
Definition A cell group originally defined by Jacobso A cell group originally defined by Jacobsohn in 1909 in humans, consisting of large, darkly staining neurons adjacent to the superior cerebellar peduncle at the midbrain-pontine junction. In 1983, Armstrong et al. recognized that these neurons in rats are cholinergic, and closely related to a second cluster of cholinergic cells in the adjacent laterodorsal tegmental nucleus. In 1987, Rye et al. defined this cell group in rats, gave references to the earlier literature, and demonstrated that it is NOT the target of the descending pallidal projection, but rather next to a region, the Midbrain Extrapyramidal Area (MEA) that does receive this input. Some modern definitions include many non-cholinergic cells that are interspersed among the cholinergic neurons within the "PPT," but those other cell groups often extend beyond the borders of the cholinergic one, have never been characterized, and many are probably unrelated to it (or have quite different functions). Hence, for this definition, we are restricting the use to the cholinergic cell group, which was originally given this name by Jacobsohn. s originally given this name by Jacobsohn.
Has default formThis property is a special property in this wiki. PONS brain region  +
Id birnlex_1437  +
Is part of Midbrain reticular formation +
Label Pedunculopontine tegmental nucleus  +
Modification dateThis property is a special property in this wiki. 2 February 2015 03:22:04  +
ModifiedDate 2 February 2015  +
NeuronamesLink  +
Page has default formThis property is a special property in this wiki. PONS brain region  +
Profile expression  +
Species Rat +, Human +, Macaca +
SuperCategory Regional part of brain  +
Synonym peduncular pontine nucleus  +, pedunculopontine nucleus  +, Nucleus tegmenti pedunculopontinus  +
Umlscui C0262306  +
Categories Regional part of brain
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110558 + About
Nucleus prepositus +, Subthalamic nucleus + AfferentProjections
Nucleus prepositus + EfferentProjections


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