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Category:Phenylalanine-4-hydroxylase
Abbrev PAH  +
CurationStatus uncurated  +
DefiningCitation Kaufman, D (1 February 1958). "A New Cofactor Required for the Enzymatic Conversion of Phenylalanine to Tyrosine.". J. Biol. Chem. 230 (230): 931–39.  +
Definition Phenylalanine hydroxylase (EC 1.14.16.1) i Phenylalanine hydroxylase (EC 1.14.16.1) is an enzyme which catalyses the reaction responsible for the addition of a hydroxyl group to the end of the 6-carbon aromatic ring of phenylalanine, such that it becomes tyrosine. Phenylalanine hydroxylase is the rate-limiting enzyme of the metabolic pathway which degrades excess phenylalanine. The PAH gene or a 1:1 ortholog thereof encodes for phenylalanine hydroxylase. eof encodes for phenylalanine hydroxylase.
Has role Enzyme +
Id PR_000012234  +
Is part of Catecholamine system +, Adrenergic system +, Dopaminergic system +, Noradrenergic system +
Label Phenylalanine-4-hydroxylase  +
Modification dateThis property is a special property in this wiki. 11 January 2014 22:36:13  +
ModifiedDate 11 January 2014  +
PMID 13525410  +
RelatedTo L-Tyrosine +, L-Phenylalanine +
SuperCategory Protein  +
Synonym Phe-4-monooxygenase  +, Phenylalanine hydroxylase  +
Categories Protein
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Epinephrine +, L-Phenylalanine +, Levodopa +, Norepinephrine +, Tetrahydrobiopterin + RelatedTo
 

 

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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.