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Category:Phenylalanine-4-hydroxylase
Abbrev PAH  +
CurationStatus uncurated  +
DefiningCitation Kaufman, D (1 February 1958). "A New Cofactor Required for the Enzymatic Conversion of Phenylalanine to Tyrosine.". J. Biol. Chem. 230 (230): 931–39.  +
Definition Phenylalanine hydroxylase (EC 1.14.16.1) i Phenylalanine hydroxylase (EC 1.14.16.1) is an enzyme which catalyses the reaction responsible for the addition of a hydroxyl group to the end of the 6-carbon aromatic ring of phenylalanine, such that it becomes tyrosine. Phenylalanine hydroxylase is the rate-limiting enzyme of the metabolic pathway which degrades excess phenylalanine. The PAH gene or a 1:1 ortholog thereof encodes for phenylalanine hydroxylase. eof encodes for phenylalanine hydroxylase.
Has role Enzyme +
Id PR_000012234  +
Is part of Catecholamine system +, Adrenergic system +, Dopaminergic system +, Noradrenergic system +
Label Phenylalanine-4-hydroxylase  +
Modification dateThis property is a special property in this wiki. 11 January 2014 22:36:13  +
ModifiedDate 11 January 2014  +
PMID 13525410  +
RelatedTo L-Tyrosine +, L-Phenylalanine +
SuperCategory Protein  +
Synonym Phe-4-monooxygenase  +, Phenylalanine hydroxylase  +
Categories Protein
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Epinephrine +, L-Phenylalanine +, Levodopa +, Norepinephrine +, Tetrahydrobiopterin + RelatedTo
 

 

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