|
|
From NeuroLex
| Abbrev
|
NIA Tissue Arrays, +
|
| Address
|
Biological Resources Branch (BRB) +,
National Institute on Aging +,
National Institutes of Health +,
7201 Wisconsin Avenue +,
GW 2C231 +,
Bethesda +,
MD 20892 +
|
| Availability
|
Public: NIA aged rodent tissue arrays are available to investigators at academic and nonprofit research institutions that are engaged in projects directly related to aging and age-related disorders. +
|
| CurationStatus
|
curated +
|
| DefiningCitation
|
http://www.nia.nih.gov/research/dab/aged-rodent-tissue-bank-handbook/tissue-arrays +
|
| Definition
|
Offer high-throughput analysis of tissue h … Offer high-throughput analysis of tissue histology and protein expression for the biogerontology research community. Each array is a 4 micron section that includes tissue cores from multiple tissues at multiple ages on one slide. The arrays are made from ethanol-fixed tissue and can be used for all techniques for which conventional tissue sections can be used.
Ages are chosen to span the life from young adult to very old age. (available ages: 4, 12, 18, 24 and 28 months of age) Images of H&E stained punches are available for Liver, Cardiac Muscle, and Brain.
The NIA aged rodent tissue arrays were developed with assistance from the National Cancer Institute (NCI) Tissue Array Research Program (TARP), led by Dr. Stephen Hewitt, Director. NCI TARP contains more information on tissue array construction, protocols for using arrays, and references.
Preparation and Product Description Tissue arrays are prepared in parallel from different sets of animals so that experiments can be conducted in duplicate, with each array using unique animals with a unique product number. The product descriptions page describes each array, including:
* Strain
* Gender
* Ages
* Tissues
* Animal Identification Numbers
* Tissues
* Animal Identification Numbers
|
| ExampleImage
|
NIA Tissue Arrays.PNG +
|
| Has default formThis property is a special property in this wiki.
|
Resource +
|
| Has role
|
Biomaterial analysis service +
|
| Id
|
nif-0000-00216 +
|
| Is part of
|
Resource:Aged Rodent Tissue Bank +
|
| Keywords
|
Aged +,
Biogerontology +,
Caloric restricted +,
Rodent +,
Protein expression +,
Tissue array +,
Tissue core +,
Histology +,
Adult +,
Old +,
Old rodent +,
C57BL/6 +,
Male +,
Female +,
Liver +,
Cardiac muscle +,
Brain +,
Tissue +,
Kidney +,
Skin +,
Frontal cortex +,
Muscle +,
Thigh +,
White adipose tissue +,
Pancreas +,
Testes +,
Prostate +,
Spleen +,
Lung +,
Heart +,
Dwarf +,
Wild type +,
Early adult +,
Middle adult +,
Late adult +,
Microarray +,
Image +
|
| Label
|
Resource:Aged Rodent Tissue Arrays +
|
| Modification dateThis property is a special property in this wiki.
|
5 January 2013 01:16:39 +
|
| ModifiedDate
|
5 January 2013 +
|
| Page has default formThis property is a special property in this wiki.
|
Resource +
|
| Processing
|
Slide +,
Tissue array +,
Tissue microarray +
|
| Related application
|
Research +
|
| Related disease
|
Aged +,
Old +,
Control +
|
| Species
|
Mouse +,
Rat +
|
| SuperCategory
|
Resource +
|
| Supporting Agency
|
National Institute on Aging +,
National Cancer Institute +,
Resource:NIH Blueprint for Neuroscience Research +
|
| Synonym
|
Aged Rodent Tissue Bank Handbook - Tissue Arrays +,
NIH Aged Rodent Tissue Bank Handbook Tissue Arrays +
|
| Categories |
Resource
|
| | No properties link to this page. |
|---|
|
|
