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Category:Resource:Beta Cell Biology Consortium
Abbrev BCBC  +
Address The Beta Cell Biology Consortium  +, Vanderbilt Center for Stem Cell Biology  +, 2213 Garland Avenue  +, 9465 MRB IV  +, Nashville  +, TN 37232-0494 Telephone: 615.936.8327 Fax: 615.322.6645  +, Region: USA  +
Availability Public +, The community can contribute to this resource +
Comment Sample type: Cell line, Embryonic stem cel Sample type: Cell line, Embryonic stem cell line Access: open; Copyrights - <br /> Reuse: closed; Copyrights - <br /> Start date: 2002 <br /> Type: disciplinary <br /> Deposit: restricted: registration <br /> (info provided by Type: Academia <br /> Participant countries: U.S. <br /> Country started: U.S. <br /> Number of partners: 50 <br /> Start date: 2001 partners: 50 <br /> Start date: 2001
CurationStatus curated  +
DefiningCitation  +
Definition Consortium that aims to facilitate interdi Consortium that aims to facilitate interdisciplinary collaborations to advance the understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. They are responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies and validation assays that are beyond the scope of any single research effort. The scientific goals for the BCBC are to: * Use cues from pancreatic development to directly differentiate pancreatic beta cells and islets from stem / progenitor cells for use in cell-replacement therapies for diabetes, * Determine how to stimulate beta cell regeneration in the adult pancreas as a basis for improving beta cell mass in diabetic patients, * Determine how to reprogram progenitor / adult cells into pancreatic beta-cells both in-vitro and in-vivo as a mean for developing cell-replacement therapies for diabetes, and * Investigate the progression of human type-1 diabetes using patient-derived cells and tissues transplanted in humanized mouse models. Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities should accelerate the pace of major new discoveries and progress within the field of beta cell biology. ess within the field of beta cell biology.
EditorialNote Each of these databases should probably have their own entry, as per NIF resource curation guidelines.
ExampleImage BCBC.PNG +
Grant Category:DK-01-014   +, Category:DK-01-17   +, Category:DK-01-18   +, Category:DK-09-011   +
Has default formThis property is a special property in this wiki. Resource  +
Has role Consortium +, Database +, Data repository +, Biospecimen repository +, Cell repository +, Organism supplier +, Experimental protocol +, Antibody supplier +
Id nlx_144143  +
Is part of Vanderbilt University; Tennessee; USA +
Keywords Pancreatic islet +, Mouse +, Beta cell +, Pancreas +, Pancreatic development +, Embryonic stem cell +, Cell line +, Genomics +, Antibody +, Adenovirus +, Functional genomics +, Mouse Embryonic stem cell line +, Mouse strain +, Protocol +, Embryonic stem cell line +, Data sharing +, Data set +, Gene expression +, Gene +, Pancreatic islet development +, Pancreatic islet function +, Basic science +, Basic research +, Cell reprogramming +, Cell regeneration +, Cell replacement +
Label Resource:Beta Cell Biology Consortium  +
Listedby Resource:One Mind Biospecimen Bank Listing +, Biobank +, +, Resource:Consortia-pedia +
Modification dateThis property is a special property in this wiki. 2 February 2015 04:27:12  +
ModifiedDate 2 February 2015  +
Page has default formThis property is a special property in this wiki. Resource  +
RelatedTo Karolinska Institutet; Stockholm; Sweden +, University of California at Los Angeles; California; USA +, Stanford University; California; USA +, University of Massachusetts Medical School; Massachusetts; USA +, Hebrew University Hadassah Medical School; Jerusalem; Israel +, Philipps-University Marburg; Marburg; Germany +, Imperial College London; London; United Kingdom +, Children's Hospital of Philadelphia; Pennsylvania; USA +, Vanderbilt University Medical Center; Tennessee; USA +, Icahn School of Medicine at Mount Sinai; New York; USA +, University of California at San Francisco; California; USA +, Massachusetts Institute of Technology; Massachusetts; USA +, Hadassah Medical Center; Jerusalem; Israel +, Resource:DanStem +, Oregon Health and Science University; Oregon; USA +, Vanderbilt University; Tennessee; USA +, University of Chicago; Illinois; USA +, University of Massachusetts; Massachusetts; USA +, University of Colorado Boulder; Colorado; USA +, Vrije Universiteit Brussel; Brussels; Belgium +, University of Geneva; Geneva; Switzerland +, University of Pennsylvania Perelman School of Medicine; Pennsylvania; USA +, Brigham and Womens Hospital; Massachusetts; USA +, Resource:McEwen Centre for Regenerative Medicine +, Seattle Childrens Research Institute; Washington; USA +, Columbia University; New York; USA +, Massachusetts General Hospital; Massachusetts; USA +, University of Texas Southwestern Medical Center; Texas; USA +, Hagedorn Research Institute; Gentofte; Denmark +, Howard Hughes Medical Institute +, Northwestern University; Illinois; USA +, Duke Medicine; North Carolina; USA +, French National Center for Scientific Research +, University of California at San Diego; California; USA +, University of Pittsburgh; Pennsylvania; USA +, University of Copenhagen; Copenhagen; Denmark +, Resource:Jackson Laboratory +, Max Planck Institute for Heart and Lung Research; Bad Nauheim; Germany +, Cincinnati Childrens Hospital Medical Center; Ohio; USA +, Indiana University; Indiana; USA +, University of Toronto; Ontario; Canada +, Harvard University; Massachusetts; USA +, Harvard Medical School; Massachusetts; USA +, Boston Childrens Hospital; Massachusetts; USA +
Related application Research  +
Related disease Type 2 diabetes +, Type 1 diabetes +, Diabetes +, Loss of beta cell mass +
Species Mouse +, Non-human animal +, Human +
SuperCategory Resource  +
Supporting Agency National Institute of Diabetes and Digestive and Kidney Diseases +
Usedby Resource:NIF Data Federation +, Resource:dkNET +
Categories Resource
hide properties that link here 
Resource:Beta Cell Genomics Ontology + Is part of
Resource:Integrated Animals +, Resource:Integrated Manually Extracted Annotation +, Resource:dkCOIN + RelatedTo
Resource:GeneSpeed- A Database of Unigene Domain Organization + Supporting Agency


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