Neurolex is being transitioned to a new system and is currently not accepting new additions. If you have additions or questions please contact us at [email protected], or submit an issue to the github issue tracker at


From NeuroLex

Jump to: navigation, search
Category:Resource:Computational Hot Spots of Protein Interfaces
CurationStatus uncurated  +
DefiningCitation  +
Definition It provides information about the evolutio It provides information about the evolutionary history of the residues on the interface and represents which residues are highly conserved on the interface. In this way, functionally and structurally important residues on the interface can be distinguished.<br /> Hotsprint contains overall properties of the interface such as number of computational hot spots on the interface, number of conserved residues on the interface, average conservation score of interface residues and buried ASA of the interface. Additionally, residues of the interface along with their position, name, conservation score, ASA in monomer, ASA in complex, type (contacting interface residue, neighboring interface residue or none) and whether the residue is computational hot spot or not information are presented.<br /> not information are presented.<br />
Has default formThis property is a special property in this wiki. Resource  +
Has role Database +
Id nif-0000-02980  +
Is part of Koc University; Istanbul; Turkey +
Keywords Evolution of proteins +, Protein residues +, Surface residues +
Label Resource:Computational Hot Spots of Protein Interfaces  +
Modification dateThis property is a special property in this wiki. 2 February 2015 05:15:10  +
ModifiedDate 2 February 2015  +
Page has default formThis property is a special property in this wiki. Resource  +
SuperCategory Resource  +
Synonym HotSprint  +
Categories Resource
hide properties that link here 
  No properties link to this page.


Enter the name of the page to start browsing from.

*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.