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Abbrev GeneMANIA  +
Address Donnelly Centre for Cellular and Biomolecular Research building  +, University of Toronto  +, Ontario  +, Canada  +
Availability Open unspecified license +, Free for academic use +
Comment org-id: genemania_team / GO data updates: every three months (or more frequently)
CurationStatus curated  +
DefiningCitation  +
Definition Data analysis service to predict the funct Data analysis service to predict the function of your favorite genes and gene sets. Indexing 1,421 association networks containing 266,984,699 interactions mapped to 155,238 genes from 7 organisms. GeneMANIA interaction networks are available for download in plain text format. GeneMANIA finds other genes that are related to a set of input genes, using a very large set of functional association data. Association data include protein and genetic interactions, pathways, co-expression, co-localization and protein domain similarity. You can use GeneMANIA to find new members of a pathway or complex, find additional genes you may have missed in your screen or find new genes with a specific function, such as protein kinases. Your question is defined by the set of genes you input. If members of your gene list make up a protein complex, GeneMANIA will return more potential members of the protein complex. If you enter a gene list, GeneMANIA will return connections between your genes, within the selected datasets. GeneMANIA suggests annotations for genes based on Gene Ontology term enrichment of highly interacting genes with the gene of interest. GeneMANIA is also a gene recommendation system. GeneMANIA is also accessible via a Cytoscape plugin, designed for power users. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible patible, Linux compatible, Unix compatible
ExampleImage GeneMANIA.PNG +
Grant Category:2007-OGI-TD-05   +
Has default formThis property is a special property in this wiki. Resource  +
Has role Data analysis service +, Software resource +, Database +
Id nlx_149159  +
Is part of University of Toronto; Ontario; Canada +
Keywords Gene +, Association data +, Protein interaction +, Genetic interaction +, Pathway +, Co-expression +, Co-localization +, Protein +, Software library +, Statistical analysis +, Term enrichment +, Analysis +, Browser +, Gene ontology +, Gene predicting +, Gene prioritization +, Database or data warehouse +, Other analysis +, Interaction browser +, Protein-protein interaction +, Interaction +
Label Resource:GeneMANIA  +
Listedby Resource:Gene Ontology Tools +
Modification dateThis property is a special property in this wiki. 11 December 2014 16:49:12  +
ModifiedDate 11 December 2014  +
PMID 20576703, 18613948, 20926419  +
Page has default formThis property is a special property in this wiki. Resource  +
PublicationLink  +
RelatedTo Resource:Cytoscape +, Resource:GO +
Species Arabidopsis thaliana +, Human +, Mouse +, Caenorhabditis elegans +, Drosophila melanogaster +, Saccharomyces cerevisiae +, Rat +
SuperCategory Resource  +
Supporting Agency Genome Canada +, Ontario Ministry of Research and Innovation +
Twitter genemania  +
Categories Resource
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Resource:PSICQUIC Registry + RelatedTo


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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.