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The database HOX Pro contain … <br />
The database HOX Pro contains information about organization, functions and evolution of gene ensembles, key roles in which play homeobox-genes.<br />
It is aimed at:<br />
1. analysis and classification of regulatory and coding regions in diverse homeobox and related genes;<br />
2. describing mutations and knock-outs of hox-genes, as well as hereditary diseases related to these genes;<br />
3. graphical representation, comparisons and classification of hox-genes expression patterns and profiles (sea urchin blastula, Drosophila blastoderm and imaginal discs, vertebrate limbs, mammalian brain, human EC cells);<br />
4. comparative analysis of organization of "hox-based" genetic networks the nematode Caenorhabditis elegans the sea urchins Strongylocentrotus purpuratus and other echinids, the fruit flies Drosophila melanogaster and D.virilis, the vertebrates chicken and mouse;<br />
5. analysis of phylogeny and evolution of homeobox genes and clusters.<br /> f homeobox genes and clusters.<br />
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