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Comment taken from DrugBank
CurationStatus uncurated  +
Curator Ab +
DefiningCitation  +
Definition Secobarbital (marketed by Eli Lilly and Co Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug. It possesses anaesthetic, anticonvulsant, sedative and hypnotic properties. In the United Kingdom, it was known as Quinalbarbitone. Pharmacology: Secobarbital, a barbiturate, is used for the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli. Little analgesia is conferred by barbiturates; their use in the presence of pain may result in excitation. Mechanism of action: Secobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged. Drug type: Approved. Small Molecule. Drug category: Adjuvants. Adjuvants, Anesthesia. Barbiturates. GABA Modulators. Hypnotics and Sedatives . GABA Modulators. Hypnotics and Sedatives
Has role Drug +, Drug of abuse role +
Id CHEBI:9073  +
Label Secobarbital  +
Modification dateThis property is a special property in this wiki. 12 August 2014 00:22:31  +
ModifiedDate 12 August 2014  +
RelatedTo GABRA1 +
SuperCategory Molecular entity  +
Synonym (+/-)-Secobarbital  +, Secobarbital Sodium  +, Secobarbitale (DCIT)  +, Secobarbitalum (INN-Latin)  +, Sodium Secobarbital  +, Sodium quinalbarbitone  +, Barbosec  +, Bipanal  +, Bipinal sodium  +, Evronal  +, Evronal Sodium  +, Evrronal  +, Hypotrol  +, Hyptran  +, Imesonal  +, Immenoctal  +, Immenox  +, Meballymal  +, Meballymal sodium  +, Meballymalum  +, Novosecobarb  +, Pramil  +, Quinalbarbital  +, Quinalbarbitone  +, Quinalbarbitone sodium  +, Quinalspan  +, Sebar  +, Seco 8  +, Secobarbitone  +, Seconal  +, Sedutain  +, Seotal  +, Somosal  +, Synate  +, Trisomnin  +
Categories Molecular entity
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Eli Lilly and Company + Keywords


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*Note: Neurolex imports many terms and their ids from existing community ontologies, e.g., the Gene Ontology. Neurolex, however, is a dynamic site and any content beyond the identifier should not be presumed to reflect the content or views of the source ontology. Users should consult with the authoritative source for each ontology for current information.