]> 2013-06-18T21:49:25-07:00 Abarelix taken from DrugBank http://www.drugbank.ca/drugs/DB00106 Synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It is marketed by Praecis Pharmaceuticals as Plenaxis. Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market. Pharmacology: Used in the palliative treatment of advanced prostate cancer. Abarelix is a luteinizing hormone agonist that results in suppression of testicular or follicular steroidogenesis. Mechanism of action: Abarelix binds to the gonadotropin releasing hormone receptor and acts as a potent inhibitor of gonadotropin secretion. Drug type: Approved. Biotech. Investigational. Withdrawn. Drug category: Anti-Testosterone Agents. Antineoplastic Agents DB00106 Abarelix 2010-02-05T00:00:00 Molecule abarelix Plenaxis Plenaxis (Praecis Pharmaceuticals) Molecule Synonym SuperCategory Gonadotrophin-releasing hormone RelatedTo ModifiedDate Label Id Drug Has role Definition DefiningCitation Ab Curator Comment