]> 2013-05-22T11:28:43-07:00 GABA-B Receptor uncurated Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and influence cells via interactions with G-proteins. GABA-B receptors are pharmacologically characterized by their insensitivity to the blocker bicuculline and sensitivity to the agonist L-baclofen. They are found both presynaptically and postsynaptically, and act variously by inhibition of adenylate cyclase, activation of phospholipase A2, activation of potassium channels, and inactivation of voltage-activated calcium channels. Year introduced: 1994 - definition from MeSH nlx_mol_090801 GABA-B Receptor 2010-01-09T00:00:00 G-protein_coupled_receptor GABAB GABA B Receptor GABA_B Gamma-aminobutyric acid-B receptor Amygdala basolateral nuclear complex pyramidal neuron Olfactory bulb (main) mitral cell Neocortex primary motor area pyramidal layer 5 corticospinal cell GHB RelatedTo NeurotransmitterReceptors G-protein coupled receptor Synonym SuperCategory ModifiedDate Label Id GABA Receptor Has role Definition CurationStatus