]> 2013-05-20T00:14:31-07:00 Resource:The Chromosome 7 Annotation Project Chromosome 7 Annotation Project Department of Genetics and Genomic Biology MaRS Centre - East Tower 101 College Street Toronto Ontario M5G 1L7 Canada uncurated http://www.chr7.org Database containing the DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented; the most up to date collation of sequence, gene, and other annotations from all databases (eg. Celera published, NCBI, Ensembl, RIKEN, UCSC) as well as unpublished data. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical genetic data, including 440 chromosome rearrangement breakpoints associated with disease. The objective of this project is to generate a comprehensive description of human chromosome 7 to facilitate biological discovery, disease gene research and medical genetic applications. There are over 360 disease-associated genes or loci on chromosome 7. A major challenge ahead will be to represent chromosome alterations, variants, and polymorphisms and their related phenotypes (or lack thereof), in an accessible way. In addition to being a primary data source, this site serves as a "weighing station" for testing community ideas and information to produce highly curated data to be submitted to other databases such as NCBI, Ensembl, and UCSC. Therefore, any useful data submitted to us will be curated and shown in this database. nif-0000-03550 Resource:Chromosome 7 Annotation Project 2013-04-22T00:00:00 Resource The Chromosome 7 Annotation Project Chromosome 7 Annotation Project Resource Synonym SuperCategory Species North American Biobank Resource:One Mind Biospecimen Bank Listing RelatedTo ModifiedDate Label Translocation Snp Segmental duplication Rearrangements Polymorphism Inversion Insertion Human Dna sequence Disease genes Deletion Clinical Chromosome 7 Chromosome Breakpoints Genome Gene annotation Gene Fish Family Expression data Duplication Keywords Hospital for Sick Children; Toronto; Canada Is part of Id Biomaterial supply Data repository Database Has role Definition DefiningCitation CurationStatus Address Abbrev